Bioisosterism is one of the leading strategies in medicinal chemistry for the design and
modification of drugs, consisting in replacing an atom or a substituent with a different atom or …

Cancer stem cells (CSCs) also known as tumour-initiating cells contribute not only to the
onset and progression of tumor in most cancer types, but also play a definitive role in …

Background Pancreatic ductal adenocarcinoma (PDAC) is a malignant pancreatic tumor
charactered by a rapid progression and high lethal rate. Hyperactivation of STAT3 signaling …

Simple Summary To the best of our knowledge, this is the first review aiming to assess the
impact of VR on the rehabilitation care of cancer survivors. We conducted a general review …

Recent advances in the development of microfluidic systems for the culture of complex and
three-dimensional cell, tissue, and organ models allow their use in toxicity studies and …

The application of chemodynamic therapy (CDT) for cancer is a serious challenge owing to
the low efficiency of the Fenton catalyst and insufficient H2O2 expression in cells. Herein, we …

The rapidly growing global burden of cancer poses a major challenge to public health and
demands a robust approach to access promising anticancer therapeutics. In parallel …

In recent years, gold nanoparticles (AuNPs) have aroused the interest of many researchers
due to their unique physicochemical and optical properties. AuNPs are being explored in a …

Centromere protein U (CENPU), a centromere-binding protein required for cellular mitosis,
has been reported to be closely associated with carcinogenesis in multiple malignancies; …

MTHFD2 is a folate‑coupled mitochondrial metabolic enzyme which has been extensively
studied in breast cancer; however, its molecular functions in this cancer remain unclear. The …