[HTML][HTML] Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment

M Zhang, W Hu, C Cai, Y Wu, J Li, S Dong - Materials Today Bio, 2022 - Elsevier
Inflammatory arthritis is a major cause of disability in the elderly. This condition causes joint
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …

[HTML][HTML] Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N Xie… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Rheumatoid arthritis microenvironment insights into treatment effect of nanomaterials

Y Zhu, T Zhao, M Liu, S Wang, S Liu, Y Yang, Y Yang… - Nano Today, 2022 - Elsevier
Rheumatoid arthritis (RA) causes a huge medical burden due to its high morbidity and
disability rate. Emerging evidences demonstrate that RA has a tumor-like microenvironment …

[HTML][HTML] Nanoenzyme engineered neutrophil-derived exosomes attenuate joint injury in advanced rheumatoid arthritis via regulating inflammatory environment

L Zhang, Z Qin, H Sun, X Chen, J Dong, S Shen… - Bioactive materials, 2022 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovitis and
destruction of cartilage, promoted by sustained inflammation. However, current treatments …

An ROS-responsive artesunate prodrug nanosystem co-delivers dexamethasone for rheumatoid arthritis treatment through the HIF-1α/NF-κB cascade regulation of …

Y Li, Q Liang, L Zhou, Y Cao, J Yang, J Li, J Liu, J Bi… - Acta biomaterialia, 2022 - Elsevier
The signaling cascade between nuclear factor-kappa B (NF-κB) and hypoxia-inducible
factor-1α (HIF-1α) can be activated by proinflammatory M1 macrophages in rheumatoid …

Dexamethasone: insights into pharmacological aspects, therapeutic mechanisms, and delivery systems

VS Madamsetty, R Mohammadinejad… - ACS biomaterials …, 2022 - ACS Publications
Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

Bioresponsive drug delivery systems for the treatment of inflammatory diseases

Y Dou, C Li, L Li, J Guo, J Zhang - Journal of Controlled Release, 2020 - Elsevier
Inflammation is intimately related to the pathogenesis of numerous acute and chronic
diseases like cardiovascular disease, inflammatory bowel disease, rheumatoid arthritis, and …

Multifunctional Janus nanoplatform for efficiently synergistic theranostics of rheumatoid arthritis

Y Liu, L Chen, Z Chen, M Liu, X Li, Y Kou, MM Hou… - ACS …, 2023 - ACS Publications
Progress has been made in the application of nanomedicine in rheumatoid arthritis (RA)
treatment. However, the whole process of monitoring and treatment of RA remains a …

[HTML][HTML] Nanomedicines for the treatment of rheumatoid arthritis: State of art and potential therapeutic strategies

Q Wang, X Qin, J Fang, X Sun - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Increasing understanding of the pathogenesis of rheumatoid arthritis (RA) has remarkably
promoted the development of effective therapeutic regimens of RA. Nevertheless, the …

A multifunctional nano-therapeutic platform based on octahedral yolk-shell Au NR@ CuS: photothermal/photodynamic and targeted drug delivery tri-combined therapy …

R Huang, C Zhang, Y Bu, Z Li, X Zheng, S Qiu… - Biomaterials, 2021 - Elsevier
Rheumatoid arthritis (RA) is a common chronic autoimmune disease that results from
synovial hyperplasia. The hyperplasia of synovium directly degrades cartilage by secreting …