Angiogenesis and inflammation are closely integrated processes in osteoarthritis (OA) and
may affect disease progression and pain. Inflammation can stimulate angiogenesis, and …

Objective In experimental collagenase‐induced osteoarthritis (OA) in the mouse, synovial
lining macrophages are crucial in mediating joint destruction. It was recently shown that …

Osteoarthritis (OA) is a whole-joint disease characterized by subchondral bone perfusion
abnormalities and neovascular invasion into the synovium and articular cartilage. In addition …

Objectives. The osteochondral junction can be a source of pain in both RA and OA. Growth
of blood vessels and nerves from the subchondral bone into articular cartilage may mediate …

Osteoarthritis (OA), one of the most common diseases among humans, is characterised
pathologically by focal areas of damage on articular cartilage centred on load-bearing …

OBJECTIVE: To evaluate the prevalence of synovitis in painful medial tibiofemoral knee
osteoarthritis (OA) and to evaluate correlation between synovitis and the structural severity …

There is an increasing body of evidence that synovitis plays a role in the progression of
osteoarthritis and that overproduction of cytokines and growth factors from the inflamed …

OBJECTIVE: Although osteoarthritis (OA) is induced by accumulated mechanical stress to
joints, little is known about the underlying molecular mechanism. To apply approaches from …

Primary disorders of tendons are common and constitute a high proportion of referrals to
rheumatologists. Certain tendons are particularly vulnerable to degenerative pathology; …

Evidence has been gathered regarding the association between angiogenesis and
inflammation in pathological situations. These two phenomena have long been coupled …