Osteoarthritis is a prevalent and disabling disease affecting an increasingly large swathe of
the world population. While clinical osteoarthritis is a late-stage condition for which disease …

Angiogenesis is a multistep process driven by a wide range of positive and negative
regulatory factors. Extracellular matrix (ECM) plays a crucial role in the regulation of this …

Introduction Cannabis-based medicines have a number of therapeutic indications, including
anti-inflammatory and analgesic effects. The endocannabinoid receptor system, including …

Objectives. Autologous platelet-secreted growth factors (GFs) may have therapeutic effects
in osteoarthritis (OA) capsular joints via multiple mechanisms. Our aim was to examine the …

Destruction and loss of articular cartilage is a central feature in most forms of arthritis
including the most common form, osteoarthritis (OA). The pathobiologic differences among …

Osteoarthritis (OA) is a common degenerative disease in mammals. However, its
pathogenesis remains unclear. Studies indicate that OA is not only an aging process that but …

Osteoarthritis (OA) is a joint disease that involves degeneration of articular cartilage, limited
intraarticular inflammation manifested by synovitis and changes in the subchondral bone …

OBJECTIVES: We hypothesised that osteochondral and synovial angiogenesis in
osteoarthritis (OA) are independent processes. We investigated whether indices of …

Osteoarthritis (OA) is the most common chronic musculoskeletal disorder. It can affect any
joint and is the most frequent single cause of disability in older adults. OA is a progressive …

Osteoarthritis (OA) is the most prevalent joint disease in older people and is characterized
by the progressive destruction of articular cartilage, synovial inflammation, changes in …