[HTML][HTML] Mechanisms of oxidized LDL-mediated endothelial dysfunction and its consequences for the development of atherosclerosis

H Jiang, Y Zhou, SM Nabavi, A Sahebkar… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis is the immuno-metabolic disease involving chronic inflammation, oxidative
stress, epigenetics, and metabolic dysfunction. There is compelling evidence suggesting …

[HTML][HTML] Understanding the connection between common stroke comorbidities, their associated inflammation, and the course of the cerebral ischemia/reperfusion …

Ł Przykaza - Frontiers in immunology, 2021 - frontiersin.org
Despite the enormous progress in the understanding of the course of the ischemic stroke
over the last few decades, a therapy that effectively protects neurovascular units (NVUs) and …

“Obesity and insulin resistance” is the component of the metabolic syndrome most strongly associated with oxidative stress

GK Jakubiak, K Osadnik, M Lejawa, T Osadnik… - Antioxidants, 2021 - mdpi.com
Metabolic syndrome (MS) is not a homogeneous entity, but this term refers to the
coexistence of factors that increase the risk for the development of type 2 diabetes and …

Inflammatory cells in atherosclerosis

M Mehu, CA Narasimhulu, DK Singla - Antioxidants, 2022 - mdpi.com
Atherosclerosis is a chronic progressive disease that involves damage to the intima,
inflammatory cell recruitment and the accumulation of lipids followed by calcification and …

Renin-angiotensin system in pathogenesis of atherosclerosis and treatment of CVD

AV Poznyak, D Bharadwaj, G Prasad… - International Journal of …, 2021 - mdpi.com
Atherosclerosis has complex pathogenesis, which involves at least three serious aspects:
inflammation, lipid metabolism alterations, and endothelial injury. There are no effective …

Inflammation: A new look at an old problem

E Gusev, Y Zhuravleva - International Journal of Molecular Sciences, 2022 - mdpi.com
Pro-inflammatory stress is inherent in any cells that are subject to damage or threat of
damage. It is defined by a number of universal components, including oxidative stress …

[HTML][HTML] Roles of macrophages in atherogenesis

L Farahi, SK Sinha, AJ Lusis - Frontiers in pharmacology, 2021 - frontiersin.org
Atherosclerosis is a chronic inflammatory disease that may ultimately lead to local
proteolysis, plaque rupture, and thrombotic vascular disease, resulting in myocardial …

Exosome-based treatment for atherosclerosis

J Heo, H Kang - International Journal of Molecular Sciences, 2022 - mdpi.com
Atherosclerosis is an inflammatory disease in which lipids accumulate on the walls of blood
vessels, thickening and clogging these vessels. It is well known that cell-to-cell …

Protective effect of olive oil microconstituents in atherosclerosis: Emphasis on PAF implicated atherosclerosis theory

S Antonopoulou, CA Demopoulos - Biomolecules, 2023 - mdpi.com
Atherosclerosis is a progressive vascular multifactorial process. The mechanisms
underlining the initiating event of atheromatous plaque formation are inflammation and …

Nitrotyrosine, nitrated lipoproteins, and cardiovascular dysfunction in patients with type 2 diabetes: What do we know and what remains to be explained?

GK Jakubiak, G Cieślar, A Stanek - Antioxidants, 2022 - mdpi.com
Diabetes mellitus (DM) is a strong risk factor for the development of cardiovascular diseases
(CVDs), which are the most important cause of morbidity and mortality in the population of …