Management of Portal Hypertension in Patients with Hepatocellular Carcinoma on Systemic Treatment: Current Evidence and Future Perspectives

V De Gaetano, M Pallozzi, L Cerrito, F Santopaolo… - Cancers, 2024 - mdpi.com
Simple Summary Portal hypertension (PH) and hepatocellular carcinoma (HCC) are major
complications of liver cirrhosis with a detrimental impact on patient outcomes that share …

Caffeine in Hepatocellular Carcinoma: Cellular Assays, Animal Experiments, and Epidemiological Investigation

L Shan, N Zhao, F Wang, D Zhai, J Liu… - Journal of Inflammation …, 2024 - Taylor & Francis
The use of caffeine in treating various liver diseases has made substantial progress in the
past decade owing to advances in science, technology, and medicine. However, whether …

Electrospun medicated gelatin/polycaprolactone Janus fibers for photothermal-chem combined therapy of liver cancer

J Zhou, Y Chen, Y Liu, T Huang, J Xing, R Ge… - International Journal of …, 2024 - Elsevier
Liver cancer is a common cancer in the world, and core-shell nanoparticles as a commonly
used combination therapy for local tumor ablation, have many shortcomings. In this study …

Ultrasound Patterns of Hepatocellular Carcinoma and Their Prognostic Impact: A Retrospective Study

C Barteselli, S Mazza, V Ravetta, FT Viera, L Veronese… - Cancers, 2023 - mdpi.com
Simple Summary Abdominal ultrasound (US) is a widely used, first-level technique for the
diagnosis of hepatocellular carcinoma (HCC). However, the prognostic meaning of different …

Methylated circulating tumor DNA in hepatocellular carcinoma: A comprehensive analysis of biomarker potential and clinical implications

Q Zhu, J Xie, W Mei, C Zeng - Cancer Treatment Reviews, 2024 - Elsevier
The intricate epigenetic landscape of hepatocellular carcinoma (HCC) is profoundly
influenced by alterations in DNA methylation patterns. Understanding these alterations is …

Hepatic extracellular ATP/adenosine dynamics in zebrafish models of alcoholic and metabolic steatotic liver disease

T Tokumaru, MEC Apolinario, N Shimizu, R Umeda… - Scientific Reports, 2024 - nature.com
Steatotic liver disease (SLD) is a burgeoning health problem predominantly associated with
excessive alcohol consumption, which causes alcohol-related liver disease (ALD), and high …

Hepatocellular Carcinoma Screening in a Contemporary Cohort of At-Risk Patients

D Daher, KS El Dahan, NE Rich, N Tayob… - JAMA Network …, 2024 - jamanetwork.com
Importance Cohort studies demonstrating an association of hepatocellular carcinoma (HCC)
screening with reduced mortality are prone to lead-time and length-time biases. Objective To …

[HTML][HTML] Enhancing HepG2 cell apoptosis with a combined nanoparticle delivery of miR-128-3p agomir and Oroxin B: A novel drug delivery approach based on PI3K …

H Wang, X Shen, X Zhu, S Zeng, S Cai - Asian Journal of Pharmaceutical …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) shows the highest morbidity among liver cancers and
accounts for a major factor inducing cancer-associated mortality globally. It is characterized …

Humanistic Health Management and Cancer: Associations of Psychology, Nutrition, and Exercise with Cancer Progression and Pathogenesis

C Li, J Zhang, P Pan, J Zhang, X Hou… - Advanced …, 2024 - Wiley Online Library
The incidence rate of cancer is increasing year by year due to the aging of the population,
unhealthy living, and eating habits. At present, surgery and medication are still the main …

[HTML][HTML] Discovery of a dual-target DYRK2 and HDAC8 inhibitor for the treatment of hepatocellular carcinoma

L Zhang, L Guan, Y Wang, MM Niu, J Yan - Biomedicine & …, 2024 - Elsevier
Dual-specificity tyrosine phosphorylation-regulated kinase 2 (DYRK2) and histone
deacetylase 8 (HDAC8) have been shown to be associated with the development of several …