Hepatocellular carcinoma (HCC), the primary form of liver cancer, is the third leading cause
of cancer-related death globally. Hernandonine is a natural alkaloid derived from Hernandia …

Hepatocellular carcinoma (HCC) shows the highest morbidity among liver cancers and
accounts for a major factor inducing cancer-associated mortality globally. It is characterized …

The incidence rate of cancer is increasing year by year due to the aging of the population,
unhealthy living, and eating habits. At present, surgery and medication are still the main …

Background The diagnosis of hepatocellular carcinoma (HCC) often experiences latency,
ultimately leading to unfavorable patient outcomes due to delayed therapeutic interventions …

Dual-specificity tyrosine phosphorylation-regulated kinase 2 (DYRK2) and histone
deacetylase 8 (HDAC8) have been shown to be associated with the development of several …

The anterior gradient protein 2 (AGR2) plays a crucial role in facilitating the formation of
protein disulfide bonds within the endoplasmic reticulum (ER). Research suggests that …

Metabolic dysfunction-associated steatotic liver disease (MASLD) and its advanced subtype,
metabolic dysfunction-associated steatohepatitis (MASH), have emerged as the most …

Enforcing a well-differentiated state on cells requires tumor suppressor p53 activation as a
key player in apoptosis induction and well differentiation. In addition, recent investigations …

Simple Summary The microenvironment of hepatocellular carcinoma is a really complex
milieu, containing a wide variety of cells with specific tasks, belonging to both the …

Simple Summary Hepatocellular carcinoma (HCC) is a common cancer and a leading cause
of cancer-related deaths worldwide. However, HCC can be effectively treated in selected …