Organ-on-a-chip for studying immune cell adhesion to liver sinusoidal endothelial cells: the potential for testing immunotherapies and cell therapy trafficking

JI Kennedy, SP Davies, PW Hewett… - Frontiers in cell and …, 2024 - frontiersin.org
Immunotherapy has changed the landscape of treatment options for patients with
hepatocellular cancer. Checkpoint inhibitors are now standard of care for patients with …

Research progress on the correlation between acetaldehyde dehydrogenase 2 and hepatocellular carcinoma development

D Yang, Y Hu, J Yang, L Tao, Y Su, Y Wu, Y Yao… - … of Pharmacology and …, 2024 - ASPET
Hepatocellular carcinoma (HCC) is the predominant pathologic type of primary liver cancer.
It is a malignant tumor of liver epithelial cells. There are many ways to treat HCC, but the …

Mechanisms of Sorafenib Resistance in Hepatocellular Carcinoma

Y Liang - Clinics and Research in Hepatology and …, 2024 - Elsevier
Liver cancer is one of the most common and devastating causes of cancer-related deaths
worldwide. Hepatocellular carcinoma (HCC) accounts for approximately 90% of primary liver …

[HTML][HTML] Assessment of Albumin-Incorporating Scores at Hepatocellular Carcinoma Diagnosis Using Machine Learning Techniques: An Evaluation of Prognostic …

M Suárez, P Martínez-Blanco, S Gil-Rojas, AM Torres… - Bioengineering, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) presents high mortality rates worldwide, with limited
evidence on prognostic factors at diagnosis. This study evaluates the utility of common …

Image-guided High-Dose-Rate Brachytherapy for Hepatocellular Carcinoma Could Be the Ultimate Ablation Tool

J Chapiro - Radiology, 2024 - pubs.rsna.org
Dr Julius Chapiro is an associate professor in radiology, hepatology, and biomedical
engineering at the Yale University School of Medicine and the principal investigator of the …

CBX1 is involved in hepatocellular carcinoma progression and resistance to sorafenib and lenvatinib via IGF-1R/AKT/SNAIL signaling pathway

SS Zheng, JF Wu, WX Wu, JW Hu, D Zhang… - Hepatology …, 2024 - Springer
Abstract Background Chromobox Homolog 1 (CBX1) plays a crucial role in the
pathogenesis of numerous diseases, including the evolution and advancement of diverse …

From MASLD to HCC: what's in the middle?

A Provera, C Vecchio, AN Sheferaw, I Stoppa… - Heliyon, 2024 - cell.com
Metabolic dysfunction associated steatotic liver disease (MASLD) is a progressive
pathological condition characterized by the accumulation of triglycerides within hepatocytes …

Histamine-related genes participate in the establishment of an immunosuppressive microenvironment and impact the immunotherapy response in hepatocellular …

X Zhang, P Zheng, B Meng, H Zhuang, B Lu… - Clinical and …, 2024 - Springer
Chronic inflammation is pivotal in the pathogenesis of hepatocellular carcinoma (HCC).
Histamine is a biologically active substance that amplifies the inflammatory and immune …

[HTML][HTML] Quantifying the natural growth rate of hepatocellular carcinoma: A real-world retrospective study in southwestern China

L Tu, H Xie, Q Li, PG Lei, PL Zhao, F Yang… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND In recent years, approximately half of the newly diagnosed cases and
mortalities attributed to hepatocellular carcinoma (HCC) have been reported in China …

[HTML][HTML] Androgen-Induced, β-Catenin-Activated Hepatocellular Adenomatosis with Spontaneous External Rupture

J Huang, T Ali, DM Feldman, ND Theise - Diagnostics, 2024 - mdpi.com
Androgens have long been recognized as oncogenic agents. They can induce both benign
and malignant hepatocellular neoplasms, including hepatocellular adenoma (HCA) and …