The future of HIV pre-exposure prophylaxis adherence: reducing barriers and increasing opportunities

JE Haberer, A Mujugira, KH Mayer - The Lancet HIV, 2023 - thelancet.com
The effectiveness of HIV pre-exposure prophylaxis (PrEP) hinges on adherence, which has
been restricted by multifaceted barriers. Uptake of PrEP has been impeded by poor access …

[HTML][HTML] Model-based predictions of protective HIV pre-exposure prophylaxis adherence levels in cisgender women

L Zhang, S Iannuzzi, A Chaturvedula, E Irungu… - Nature medicine, 2023 - nature.com
Most human immunodeficiency virus (HIV) infections occur in cisgender women in resource-
limited settings. In women, self-protection with emtricitabine/tenofovir disoproxil fumarate pre …

[HTML][HTML] High PrEP uptake and objective longitudinal adherence among HIV-exposed women with personal or partner plans for pregnancy in rural Uganda: A cohort …

LT Matthews, EC Atukunda, M Owembabazi… - PLoS …, 2023 - journals.plos.org
Background In Uganda, fertility rates and adult HIV prevalence are high, and many women
conceive with partners living with HIV. Pre-exposure prophylaxis (PrEP) reduces HIV …

The impact of prevention‐effective PrEP use on HIV incidence: a mathematical modelling study

DA Roberts, D Bridenbecker, JE Haberer… - African Journal of …, 2022 - journals.lww.com
Introduction: Models that project the impact and cost-effectiveness of HIV pre-exposure
prophylaxis (PrEP) must specify how PrEP use aligns with HIV exposure. We hypothesized …

[HTML][HTML] Effect of HIV self-testing on PrEP adherence among gender-diverse sex workers in Uganda: a randomized trial

A Mujugira, A Nakyanzi, MS Nabaggala… - JAIDS Journal of …, 2022 - journals.lww.com
Background: HIV self-testing (HIVST) and pre-exposure prophylaxis (PrEP) are
complementary tools that could empower sex workers to control their HIV protection, but few …

[HTML][HTML] Awareness of Heightened Sexual and Behavioral Vulnerability as a Trigger for PrEP Resumption Among Adolescent Girls and Young Women in East and …

K Reddy, T Palanee-Phillips, R Heffron - Current HIV/AIDS Reports, 2023 - Springer
Abstract Purpose of Review East and Southern Africa are the epicenter of the HIV epidemic.
High HIV incidence rates among adolescent girls and young women (AGYW) remain stable …

[HTML][HTML] Acceptability and feasibility of long-term, real-time electronic adherence monitoring of HIV pre-exposure prophylaxis (PrEP) use among young women in …

VA Ogello, BK Rono, K Ngure, E Sedah, NB Thuo… - Plos one, 2024 - journals.plos.org
Real-time electronic adherence monitoring involves “smart” pill boxes that record and
monitor openings as a proxy for pill taking and may be useful in understanding and …

A community‐based dynamic choice model for HIV prevention improves PrEP and PEP coverage in rural Uganda and Kenya: a cluster randomized trial

ER Kakande, J Ayieko, H Sunday… - Journal of the …, 2023 - Wiley Online Library
Introduction Optimizing HIV prevention may require structured approaches for providing
client‐centred choices as well as community‐based entry points and delivery. We evaluated …

My Way: development and preliminary evaluation of a novel delivery system for PrEP and other sexual health needs of young women in Western Kenya

JE Haberer, K Oware, L Juma… - Journal of the …, 2024 - Wiley Online Library
Introduction Young women in sub‐Saharan Africa are a priority population for HIV
prevention, yet challenges with adherence and persistence to HIV pre‐exposure prophylaxis …

Integrating pre-exposure prophylaxis of HIV infection into family planning services: a scoping review

CI Gotsche, PS Steyn, M Narasimhan… - BMJ sexual & …, 2023 - srh.bmj.com
Introduction The aim of this review was to map evidence of integrating pre-exposure
prophylaxis (PrEP) for HIV prevention into family planning services. A comprehensive …