Gender differences in the effects of cardiovascular drugs

J Tamargo, G Rosano, T Walther… - European Heart …, 2017 - academic.oup.com
An initiation-promotion protocol was used to test the hypothesis that unleaded gasoline (UG)
vapor acts as a liver tumor promoter in female mice under exposure conditions in which UG …

Clinical advances in sex-and gender-informed medicine to improve the health of all: a review

D Bartz, T Chitnis, UB Kaiser… - JAMA internal …, 2020 - jamanetwork.com
Importance Biological sex and sociocultural gender represent major sources of diversity
among patients, and recent research has shown the association of sex and gender with …

Sex differences in adverse drug reactions reported to the National Pharmacovigilance Centre in the Netherlands: An explorative observational study

ST de Vries, P Denig, C Ekhart… - British journal of …, 2019 - Wiley Online Library
Aims: We aimed to assess and characterize sex differences in adverse drug reactions
(ADRs) reported to the national pharmacovigilance centre in the Netherlands while …

Sex differences in alcohol use disorder

R Agabio, C Pisanu, G Luigi Gessa… - Current medicinal …, 2017 - ingentaconnect.com
Background: Alcohol use disorder (AUD) is a common and disabling mental disorder
associated with a significant burden of medical consequences and high socioeconomic …

Sex-specific cardiovascular risks of cancer and its therapies

NS Wilcox, SJ Rotz, MK Mullen, EJ Song… - Circulation …, 2022 - Am Heart Assoc
In both cardiovascular disease and cancer, there are established sex-based differences in
prevalence and outcomes. Males and females may also differ in terms of risk of cardiotoxicity …

The role of pharmacogenomics in adverse drug reactions

R Cacabelos, N Cacabelos, JC Carril - Expert Review of Clinical …, 2019 - Taylor & Francis
ABSTRACT Introduction: Adverse drug reactions (ADRs) are a major health concern
worldwide. There are multiple causes of ADRs, some of which are preventable …

[HTML][HTML] A sex-and gender-based analysis of adverse drug reactions: a scoping review of pharmacovigilance databases

AC Brabete, L Greaves, M Maximos, E Huber, A Li… - Pharmaceuticals, 2022 - mdpi.com
Drug-related adverse events or adverse drug reactions (ADRs) are currently partially or
substantially under-reported. ADR reporting systems need to expand their focus to include …

[HTML][HTML] Gender-neutral mental health research is sex and gender biased

LM Howard, AM Ehrlich, F Gamlen, S Oram - The Lancet Psychiatry, 2017 - thelancet.com
Few would disagree that sex is of relevance in understanding and treating mental disorders,
but there seems to be less consensus on the extent to which researchers should consider …

Medication regimen complexity and polypharmacy as factors associated with all-cause mortality in older people: a population-based cohort study

BC Wimmer, JS Bell, J Fastbom… - Annals of …, 2016 - journals.sagepub.com
Objectives: To investigate whether medication regimen complexity and/or polypharmacy are
associated with all-cause mortality in older people. Methods: This was a population-based …

Sex-related differences in pharmacokinetics and pharmacodynamics of frequently prescribed drugs: a review of the literature

A Farkouh, T Riedl, R Gottardi, M Czejka… - Advances in …, 2020 - Springer
While there is considerable evidence about sex-related differences between men and
women in drug metabolism, efficacy and safety of frequently prescribed drugs such as …