[HTML][HTML] Effect of stromal cells in tumor microenvironment on metastasis initiation
The cellular environment where tumor cells reside is called the tumor microenvironment
(TME), which consists of borders, blood vessels, lymph vessels, extracellular matrix (ECM) …
(TME), which consists of borders, blood vessels, lymph vessels, extracellular matrix (ECM) …
The role of chronic inflammation in the development of breast cancer
DN Danforth - Cancers, 2021 - mdpi.com
Simple Summary Chronic inflammation is an important cause of multiple cancers. While
chronic inflammation is present in breast cancer and may influence its outcome, its role in …
chronic inflammation is present in breast cancer and may influence its outcome, its role in …
[HTML][HTML] Aging-associated alterations in mammary epithelia and stroma revealed by single-cell RNA sequencing
CMC Li, H Shapiro, C Tsiobikas, LM Selfors, H Chen… - Cell reports, 2020 - cell.com
Aging is closely associated with increased susceptibility to breast cancer, yet there have
been limited systematic studies of aging-induced alterations in the mammary gland. Here …
been limited systematic studies of aging-induced alterations in the mammary gland. Here …
[HTML][HTML] Role of tumor microenvironment in triple-negative breast cancer and its prognostic significance
T Yu, G Di - Chinese Journal of Cancer Research, 2017 - ncbi.nlm.nih.gov
Breast cancer has been shown to live in the tumor microenvironment, which consists of not
only breast cancer cells themselves but also a significant amount of pathophysiologically …
only breast cancer cells themselves but also a significant amount of pathophysiologically …
Three-dimensional cell cultures: the bridge between in vitro and in vivo models
O Urzì, R Gasparro, E Costanzo, A De Luca… - International Journal of …, 2023 - mdpi.com
Although historically, the traditional bidimensional in vitro cell system has been widely used
in research, providing much fundamental information regarding cellular functions and …
in research, providing much fundamental information regarding cellular functions and …
Chemokines and chemokine receptors: A new strategy for breast cancer therapy
H Liu, Z Yang, W Lu, Z Chen, L Chen, S Han… - Cancer …, 2020 - Wiley Online Library
Chemokines and chemokine receptors not only participate in the development of tissue
differentiation, hematopoiesis, inflammation, and immune regulation but also play an …
differentiation, hematopoiesis, inflammation, and immune regulation but also play an …
The multifaceted link between inflammation and human diseases
P Rajendran, YF Chen, YF Chen… - Journal of cellular …, 2018 - Wiley Online Library
Increasing reports on epidemiological, diagnostic, and clinical studies suggest that
dysfunction of the inflammatory reaction results in chronic illnesses such as cancer, arthritis …
dysfunction of the inflammatory reaction results in chronic illnesses such as cancer, arthritis …
The complex interaction between the tumor micro-environment and immune checkpoints in breast cancer
V Barriga, N Kuol, K Nurgali, V Apostolopoulos - Cancers, 2019 - mdpi.com
The progression of breast cancer and its association with clinical outcome and treatment
remain largely unexplored. Accumulating data has highlighted the interaction between cells …
remain largely unexplored. Accumulating data has highlighted the interaction between cells …
Regulation of embryonic and postnatal development by the CSF-1 receptor
V Chitu, ER Stanley - Current topics in developmental biology, 2017 - Elsevier
Macrophages are found in all tissues and regulate tissue morphogenesis during
development through trophic and scavenger functions. The colony stimulating factor-1 (CSF …
development through trophic and scavenger functions. The colony stimulating factor-1 (CSF …
Adverse outcome pathways for ionizing radiation and breast cancer involve direct and indirect DNA damage, oxidative stress, inflammation, genomic instability, and …
JS Helm, RA Rudel - Archives of toxicology, 2020 - Springer
Abstract Knowledge about established breast carcinogens can support improved and
modernized toxicological testing methods by identifying key mechanistic events. Ionizing …
modernized toxicological testing methods by identifying key mechanistic events. Ionizing …