[HTML][HTML] Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics
U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra… - Genes & …, 2023 - Elsevier
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …
produce aggressive malignancies that causes millions of deaths every year. With the new …
Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities
There has been a revolution in nanotechnology and nanomedicine. Since 1980, there has
been a remarkable increase in approved nano-based pharmaceutical products. These novel …
been a remarkable increase in approved nano-based pharmaceutical products. These novel …
[HTML][HTML] Biomaterials from the sea: Future building blocks for biomedical applications
M Wan, W Qin, C Lei, Q Li, M Meng, M Fang, W Song… - Bioactive Materials, 2021 - Elsevier
Marine resources have tremendous potential for developing high-value biomaterials. The
last decade has seen an increasing number of biomaterials that originate from marine …
last decade has seen an increasing number of biomaterials that originate from marine …
[HTML][HTML] On the design principles of peptide–drug conjugates for targeted drug delivery to the malignant tumor site
Cancer is the second leading cause of death affecting nearly one in two people, and the
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …
[HTML][HTML] Approved and marketed nanoparticles for disease targeting and applications in COVID-19
AAH Abdellatif, AF Alsowinea - Nanotechnology Reviews, 2021 - degruyter.com
Nano-based systems can be used to transport active medicinal products to specific parts of
the body. Most challenges with drug delivery, such as low water solubility and poor …
the body. Most challenges with drug delivery, such as low water solubility and poor …
[HTML][HTML] Direct targeting options for STAT3 and STAT5 in cancer
Signal transducer and activator of transcription (STAT) 3 and STAT5 are important
transcription factors that are able to mediate or even drive cancer progression through …
transcription factors that are able to mediate or even drive cancer progression through …
Hyaluronic acid-based prodrug nanomedicines for enhanced tumor targeting and therapy: A review
R Zhang, X Zhao, A Jia, C Wang, H Jiang - International Journal of …, 2023 - Elsevier
Hyaluronic acid (HA) represents a natural polysaccharide which has attracted significant
attention owing to its improved tumor targeting capacity, enzyme degradation capacity, and …
attention owing to its improved tumor targeting capacity, enzyme degradation capacity, and …
Use of nano engineered approaches to overcome the stromal barrier in pancreatic cancer
While chemotherapy is the only approved non-surgical option for the majority of pancreatic
cancer patients, it rarely results in a cure. The failure to respond to chemotherapy is due to …
cancer patients, it rarely results in a cure. The failure to respond to chemotherapy is due to …
Prussian blue nanozymes: progress, challenges, and opportunities
H He, M Long, Y Duan, N Gu - Nanoscale, 2023 - pubs.rsc.org
Prussian Blue Nanozymes (PBNZs) have emerged as highly efficient agents for reactive
oxygen species (ROS) elimination, owing to their multiple enzyme-like properties …
oxygen species (ROS) elimination, owing to their multiple enzyme-like properties …
Targeting acute myeloid leukemia using sphingosine kinase 1 inhibitor-loaded liposomes
TM Nguyen, M Jambhrunkar, SS Wong… - Molecular …, 2023 - ACS Publications
Acute myeloid leukemia (AML) kills 75% of patients and represents a major clinical
challenge with a need to improve on current treatment approaches. Targeting sphingosine …
challenge with a need to improve on current treatment approaches. Targeting sphingosine …