[HTML][HTML] Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics

U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra… - Genes & …, 2023 - Elsevier
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …

Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities

F Farjadian, A Ghasemi, O Gohari, A Roointan… - …, 2019 - Future Medicine
There has been a revolution in nanotechnology and nanomedicine. Since 1980, there has
been a remarkable increase in approved nano-based pharmaceutical products. These novel …

[HTML][HTML] Biomaterials from the sea: Future building blocks for biomedical applications

M Wan, W Qin, C Lei, Q Li, M Meng, M Fang, W Song… - Bioactive Materials, 2021 - Elsevier
Marine resources have tremendous potential for developing high-value biomaterials. The
last decade has seen an increasing number of biomaterials that originate from marine …

[HTML][HTML] On the design principles of peptide–drug conjugates for targeted drug delivery to the malignant tumor site

EI Vrettos, G Mező, AG Tzakos - Beilstein journal of organic …, 2018 - beilstein-journals.org
Cancer is the second leading cause of death affecting nearly one in two people, and the
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …

[HTML][HTML] Approved and marketed nanoparticles for disease targeting and applications in COVID-19

AAH Abdellatif, AF Alsowinea - Nanotechnology Reviews, 2021 - degruyter.com
Nano-based systems can be used to transport active medicinal products to specific parts of
the body. Most challenges with drug delivery, such as low water solubility and poor …

[HTML][HTML] Direct targeting options for STAT3 and STAT5 in cancer

A Orlova, C Wagner, ED de Araujo, D Bajusz… - Cancers, 2019 - mdpi.com
Signal transducer and activator of transcription (STAT) 3 and STAT5 are important
transcription factors that are able to mediate or even drive cancer progression through …

Hyaluronic acid-based prodrug nanomedicines for enhanced tumor targeting and therapy: A review

R Zhang, X Zhao, A Jia, C Wang, H Jiang - International Journal of …, 2023 - Elsevier
Hyaluronic acid (HA) represents a natural polysaccharide which has attracted significant
attention owing to its improved tumor targeting capacity, enzyme degradation capacity, and …

Use of nano engineered approaches to overcome the stromal barrier in pancreatic cancer

H Meng, AE Nel - Advanced drug delivery reviews, 2018 - Elsevier
While chemotherapy is the only approved non-surgical option for the majority of pancreatic
cancer patients, it rarely results in a cure. The failure to respond to chemotherapy is due to …

Prussian blue nanozymes: progress, challenges, and opportunities

H He, M Long, Y Duan, N Gu - Nanoscale, 2023 - pubs.rsc.org
Prussian Blue Nanozymes (PBNZs) have emerged as highly efficient agents for reactive
oxygen species (ROS) elimination, owing to their multiple enzyme-like properties …

Targeting acute myeloid leukemia using sphingosine kinase 1 inhibitor-loaded liposomes

TM Nguyen, M Jambhrunkar, SS Wong… - Molecular …, 2023 - ACS Publications
Acute myeloid leukemia (AML) kills 75% of patients and represents a major clinical
challenge with a need to improve on current treatment approaches. Targeting sphingosine …