Galectin-9 has non-apoptotic cytotoxic activity toward acute myeloid leukemia independent of cytarabine resistance

G Choukrani, N Visser, N Ustyanovska Avtenyuk… - Cell Death …, 2023 - nature.com
Acute myeloid leukemia (AML) is a malignancy still associated with poor survival rates,
among others, due to frequent occurrence of therapy-resistant relapse after standard-of-care …

Cytarabine prevents neuronal damage by enhancing AMPK to stimulate PINK1/Parkin-involved mitophagy In Parkinson's disease model

L Li, Y Zhang, Z Chen, C Xu, Z Xu, H Pei… - European Journal of …, 2024 - Elsevier
Parkinson's disease (PD) is a common age-related neurodegenerative disorder, which may
be largely due to the mitochondrial dysfunction and impaired mitophagy. Thus, it is of great …

Long‐term outcomes of children with extracutaneous juvenile xanthogranulomas in Japan

M Maeda, A Morimoto, Y Shioda, T Asano… - Pediatric Blood & …, 2020 - Wiley Online Library
Background Juvenile xanthogranuloma (JXG) is the most common non‐Langerhans cell
histiocytosis in children. The mortality and morbidity of JXG with extracutaneous lesions …

Radotinib enhances cytarabine (Ara-C)-induced acute myeloid leukemia cell death

SK Heo, EK Noh, HM Yu, DK Kim, HJ Seo, YJ Lee… - BMC cancer, 2020 - Springer
Background Acute myeloid leukemia (AML) is a heterogeneous disease that frequently
relapses after standard chemotherapy. Therefore, there is a need for the development of …

Utilizing an endogenous progesterone receptor reporter gene for drug screening and mechanistic study in endometrial cancer

Y Li, W Zhou, X Meng, SD Murray, L Li, A Fronk… - Cancers, 2022 - mdpi.com
Simple Summary In this study, we generate an innovative endogenous progesterone
receptor (PR) reporter gene containing endometrial cancer cell lines and use this tool to …

A screening of antineoplastic drugs for acute myeloid leukemia reveals contrasting immunogenic effects of etoposide and fludarabine

D Ocadlikova, C Iannarone, AR Redavid… - International Journal of …, 2020 - mdpi.com
Background: Recent evidence demonstrated that the treatment of acute myeloid leukemia
(AML) cells with daunorubicin (DNR) but not cytarabine (Ara-C) results in immunogenic cell …

Daunorubicin induces GLI1‑dependent apoptosis in colorectal cancer cell lines

BR Kim, DY Kim, NL Tran, BG Kim… - International …, 2024 - spandidos-publications.com
Daunorubicin, also known as daunomycin, is a DNA‑targeting anticancer drug that is used
as chemotherapy, mainly for patients with leukemia. It has also been shown to have …

Mangiferin induces immune responses and evaluates the survival rate in WEHI‐3 cell generated mouse leukemia in vivo

HS Shang, CJ Chen, YL Shih, SF Peng… - Environmental …, 2021 - Wiley Online Library
Mangiferin is a naturally occurring polyphenol, widely distributed in Thymeraceae families,
and presents pharmacological activity, including anti‐cancer activities in many human …

Classic and targeted anti‐leukaemic agents interfere with the cholesterol biogenesis metagene in acute myeloid leukaemia: therapeutic implications

F Chen, X Wu, C Niculite, M Gilca… - Journal of Cellular …, 2020 - Wiley Online Library
Despite significant advances in deciphering the molecular landscape of acute myeloid
leukaemia (AML), therapeutic outcomes of this haematological malignancy have only …

Gene SH3BGRL3 regulates acute myeloid leukemia progression through circRNA_0010984 based on competitive endogenous RNA mechanism

X Yang, Y Wang, S Rong, J An, X Lan, B Yin… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Acute myeloid leukemia (AML) is a malignant proliferative disease affecting the
bone marrow hematopoietic system and has a poor long-term outcome. Exploring genes …