The survival of the human malaria parasite Plasmodium falciparum under the
physiologically distinct environments associated with their development in the cold-blooded …

Cellular proteostasis requires a network of molecular chaperones and co-chaperones,
which facilitate the correct folding and assembly of other proteins, or the degradation of …

We investigate thiazolyl-pyrazoline derivatives as promising drugs for the anti-malarial.
Protein kinase G is a primary target for treating malaria due to its essential role in …

Plasmodium falciparum is a unicellular, intracellular protozoan parasite, and the causative
agent of malaria in humans, a deadly vector borne infectious disease. A key phase of …

Plasmodium falciparum is a unicellular protozoan parasite and causative agent of the most
severe form of malaria in humans. The malaria parasite has had to develop sophisticated …

Malaria still persists as one of the deadliest infectious disease having a huge morbidity and
mortality affecting the higher population of the world. Structure and ligand-based drug …

The heat shock protein 40 (Hsp40) family, also called J domain proteins (JDPs), regulate
their Hsp70 partners by ensuring that they are engaging the right substrate at the right time …

During its complex life cycle, the malaria parasite survives dramatic environmental stresses,
including large temperature shifts. Protein prenylation is required during asexual replication …

Plasmodium falciparum is responsible for the most severe and deadliest human malaria
infection. The most serious complication of this infection is cerebral malaria. Among the …

The main agent of human malaria, the protozoa, Plasmodium falciparum is known to infect
liver cells, subsequently invading the host erythrocyte, leading to the manifestation of clinical …