Pathophysiology and therapeutic approaches to acute decompensated heart failure
JN Njoroge, JR Teerlink - Circulation research, 2021 - Am Heart Assoc
Acute decompensated heart failure (ADHF) is one of the leading admission diagnoses
worldwide, yet it is an entity with incompletely understood pathophysiology and limited …
worldwide, yet it is an entity with incompletely understood pathophysiology and limited …
[HTML][HTML] Molecular mechanisms for ketone body metabolism, signaling functions, and therapeutic potential in cancer
CY Hwang, W Choe, KS Yoon, J Ha, SS Kim, EJ Yeo… - Nutrients, 2022 - mdpi.com
The ketone bodies (KBs) β-hydroxybutyrate and acetoacetate are important alternative
energy sources for glucose during nutrient deprivation. KBs synthesized by hepatic …
energy sources for glucose during nutrient deprivation. KBs synthesized by hepatic …
Mechanistic insights of empagliflozin in nondiabetic patients with HFrEF: from the EMPA-TROPISM study
JA Requena-Ibáñez, CG Santos-Gallego… - Heart Failure, 2021 - jacc.org
Objectives The goal of this study was to evaluate the effect of empagliflozin, in addition to
optimal medical treatment, on epicardial adipose tissue (EAT), interstitial myocardial fibrosis …
optimal medical treatment, on epicardial adipose tissue (EAT), interstitial myocardial fibrosis …
Cardio-onco-metabolism: metabolic remodelling in cardiovascular disease and cancer
Cardiovascular disease and cancer are the two leading causes of morbidity and mortality in
the world. The emerging field of cardio-oncology has revealed that these seemingly …
the world. The emerging field of cardio-oncology has revealed that these seemingly …
Metabolomic profiling of the effects of dapagliflozin in heart failure with reduced ejection fraction: DEFINE-HF
Background: Sodium-glucose cotransporter-2 inhibitors are foundational therapy in patients
with heart failure with reduced ejection fraction (HFrEF), but underlying mechanisms of …
with heart failure with reduced ejection fraction (HFrEF), but underlying mechanisms of …
[HTML][HTML] The ketogenic diet and cardiovascular diseases
D Dyńka, K Kowalcze, A Charuta, A Paziewska - Nutrients, 2023 - mdpi.com
The most common and increasing causes of death worldwide are cardiovascular diseases
(CVD). Taking into account the fact that diet is a key factor, it is worth exploring this aspect of …
(CVD). Taking into account the fact that diet is a key factor, it is worth exploring this aspect of …
Masticatory system–inspired microneedle theranostic platform for intelligent and precise diabetic management
J Yang, S Zheng, D Ma, T Zhang, X Huang… - Science …, 2022 - science.org
Integrated systems for diabetic theranostics present advanced technology to regulate
diabetes yet still have critical challenges in terms of accuracy, long-term monitoring, and …
diabetes yet still have critical challenges in terms of accuracy, long-term monitoring, and …
Cardioprotective effect of empagliflozin and circulating ketone bodies during acute myocardial infarction
CG Santos-Gallego, JA Requena-Ibáñez… - Circulation …, 2023 - Am Heart Assoc
Background: SGLT2i (sodium-glucose cotransporter-2 inhibitors) improve clinical outcomes
in patients with heart failure, but the mechanisms of action are not completely understood …
in patients with heart failure, but the mechanisms of action are not completely understood …
Cardiac metabolism in HFpEF: from fuel to signalling
Heart failure (HF) is marked by distinctive changes in myocardial uptake and utilization of
energy substrates. Among the different types of HF, HF with preserved ejection fraction …
energy substrates. Among the different types of HF, HF with preserved ejection fraction …
[HTML][HTML] The effect of ketogenic diet on shared risk factors of cardiovascular disease and cancer
Cardiovascular disease (CVD) and cancer are the first and second leading causes of death
worldwide, respectively. Epidemiological evidence has demonstrated that the incidence of …
worldwide, respectively. Epidemiological evidence has demonstrated that the incidence of …