Functional extracellular vesicles for regenerative medicine
The unique biological characteristics and promising clinical potential of extracellular
vesicles (EVs) have galvanized EV applications for regenerative medicine. Recognized as …
vesicles (EVs) have galvanized EV applications for regenerative medicine. Recognized as …
Identification of storage conditions stabilizing extracellular vesicles preparations
Extracellular vesicles (EVs) play a key role in many physiological and pathophysiological
processes and hold great potential for therapeutic and diagnostic use. Despite significant …
processes and hold great potential for therapeutic and diagnostic use. Despite significant …
The evolving regulatory landscape in regenerative medicine
DJ Beetler, DN Di Florio, EW Law, CM Groen… - Molecular aspects of …, 2023 - Elsevier
Regenerative medicine as a field has emerged as a new component of modern medicine
and medical research that encompasses a wide range of products including cellular and …
and medical research that encompasses a wide range of products including cellular and …
Enhancing extracellular vesicle analysis by integration of large-volume sample stacking in capillary electrophoresis with asymmetrical flow field-flow fractionation
Extracellular vesicles (EVs) play important roles in cell–cell communication and pathological
development. Cargo profiling for the EVs present in clinical specimens can provide valuable …
development. Cargo profiling for the EVs present in clinical specimens can provide valuable …
[HTML][HTML] Comprehensive proteomic profiling of plasma and serum phosphatidylserine-positive extracellular vesicles reveals tissue-specific proteins
S Muraoka, M Hirano, J Isoyama, S Nagayama… - IScience, 2022 - cell.com
Extracellular vesicles (EVs) are ubiquitously secreted by almost all tissues and carry many
cargoes, including proteins, RNAs, and lipids, which are related to various biological …
cargoes, including proteins, RNAs, and lipids, which are related to various biological …
Comparison of extracellular vesicle isolation processes for therapeutic applications
S Williams, M Fernandez-Rhodes… - Journal of Tissue …, 2023 - journals.sagepub.com
While extracellular vesicles (EVs) continue to gain interest for therapeutic applications, their
clinical translation is limited by a lack of optimal isolation methods. We sought to determine …
clinical translation is limited by a lack of optimal isolation methods. We sought to determine …
From conventional to microfluidic: progress in extracellular vesicle separation and individual characterization
M Chen, S Lin, C Zhou, D Cui, H Haick… - Advanced Healthcare …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are nanoscale membrane vesicles, which contain a wide variety
of cargo such as proteins, miRNAs, and lipids. A growing body of evidence suggests that …
of cargo such as proteins, miRNAs, and lipids. A growing body of evidence suggests that …
[HTML][HTML] Size-exclusion chromatography combined with ultrafiltration efficiently isolates extracellular vesicles from human blood samples in health and disease
C Franco, A Ghirardello, L Bertazza… - International Journal of …, 2023 - mdpi.com
There is still a need for an efficient method for the isolation of extracellular vesicles (EVs)
from human blood that provides a reliable yield with acceptable purity. Blood is a source of …
from human blood that provides a reliable yield with acceptable purity. Blood is a source of …
[HTML][HTML] Extracellular vesicles-ceRNAs as ovarian cancer biomarkers: looking into circRNA-miRNA-mRNA code
G Cammarata, N Barraco, I Giusti, V Gristina, V Dolo… - Cancers, 2022 - mdpi.com
Simple Summary Patients with ovarian cancer have a very poor chance of long-term
survival, usually due to advanced disease at the time of diagnosis. Emerging evidence …
survival, usually due to advanced disease at the time of diagnosis. Emerging evidence …
[HTML][HTML] Liquid biopsies to occult brain metastasis
Brain metastasis (BrM) is a major problem associated with cancer-related mortality, and
currently, no specific biomarkers are available in clinical settings for early detection. Liquid …
currently, no specific biomarkers are available in clinical settings for early detection. Liquid …