The cardio-renal-metabolic connection: a review of the evidence

M Marassi, GP Fadini - Cardiovascular Diabetology, 2023 - Springer
Abstract Type 2 diabetes (T2D), cardiovascular disease (CVD) and chronic kidney disease
(CKD), are recognized among the most disruptive public health issues of the current century …

Diabetic microvascular disease in non-classical beds: the hidden impact beyond the retina, the kidney, and the peripheral nerves

D Mauricio, M Gratacòs, J Franch-Nadal - Cardiovascular Diabetology, 2023 - Springer
Diabetes microangiopathy, a hallmark complication of diabetes, is characterised by
structural and functional abnormalities within the intricate network of microvessels beyond …

Eph-ephrin signaling couples endothelial cell sorting and arterial specification

J Stewen, K Kruse, AT Godoi-Filip, Zenia… - Nature …, 2024 - nature.com
Cell segregation allows the compartmentalization of cells with similar fates during
morphogenesis, which can be enhanced by cell fate plasticity in response to local molecular …

The dual angiogenesis effects via Nrf2/HO-1 signaling pathway of melatonin nanocomposite scaffold on promoting diabetic bone defect repair

T Chen, Z Wu, Q Hou, Y Mei, K Yang, J Xu… - International Journal of …, 2024 - Taylor & Francis
Purpose Given the escalating prevalence of diabetes, the demand for specific bone graft
materials is increasing, owing to the greater tendency towards bone defects and more …

Framework Nucleic Acids‐Based VEGF Signaling Activating System for Angiogenesis: A Dual Stimulation Strategy

Y Ge, Q Wang, Y Yao, Q Xin, J Sun, W Chen… - Advanced …, 2024 - Wiley Online Library
Angiogenesis is crucial for tissue engineering, wound healing, and regenerative medicine.
Nanomaterials constructed based on specific goals can be employed to activate …

Unveiling the pathogenesis and therapeutic approaches for diabetic nephropathy: insights from panvascular diseases

X Zhang, J Zhang, Y Ren, R Sun, X Zhai - Frontiers in Endocrinology, 2024 - frontiersin.org
Diabetic nephropathy (DN) represents a significant microvascular complication in diabetes,
entailing intricate molecular pathways and mechanisms associated with cardiorenal …

Trends and disparities in China's cardiovascular disease burden from 1990 to 2019

J Zhang, H Tong, L Jiang, Y Zhang, J Hu - Nutrition, Metabolism and …, 2023 - Elsevier
Background and aims In order to find the exact strategies in the prevention of cardiovascular
diseases (CVD), it is necessary to assess their risk factors systematically. Here, we used the …

Molecular mechanisms of diabetic heart disease: Insights from transcriptomic technologies

M Conning-Rowland… - Diabetes & Vascular …, 2023 - journals.sagepub.com
Over half a billion adults across the world have diabetes mellitus (DM). This has a wide-
ranging impact on their health, including more than doubling their risk of major …

Identification of a non-invasive urinary exosomal biomarker for diabetic nephropathy using data-independent acquisition proteomics

X Ding, D Zhang, Q Ren, Y Hu, J Wang, J Hao… - International Journal of …, 2023 - mdpi.com
Diabetic nephropathy (DN), as the one of most common complications of diabetes, is
generally diagnosed based on a longstanding duration, albuminuria, and decreased kidney …

Type 2 diabetic mellitus related osteoporosis: focusing on ferroptosis

Y Chen, W Zhao, A Hu, S Lin, P Chen, B Yang… - Journal of Translational …, 2024 - Springer
With the aging global population, type 2 diabetes mellitus (T2DM) and osteoporosis (OP) are
becoming increasingly prevalent. Diabetic osteoporosis (DOP) is a metabolic bone disorder …