Tumor development and metastasis are facilitated by the complex interactions between
cancer cells and their microenvironment, which comprises stromal cells and extracellular …

Immune cell-based therapies are a rapidly emerging class of new medicines that directly
treat and prevent targeted cancer. However multiple biological barriers impede the activity of …

Background Immunosuppression is a significant factor contributing to the poor prognosis of
cancer. S100P, a member of the S100 protein family, has been implicated in various …

Existing immune checkpoint inhibitors focus on activating T cells and show limited
effectiveness in gastric cancer (GC). SIGLEC10 is identified as a novel tumor-associated …

The cancer microenvironment, or tumor microenvironment (TME), describes the
noncancerous cells present in the tumor, such as fibroblasts, immune cells, and cells that …

Natural killer cells are members of the innate immune system and promote cytotoxic activity
against tumor or infected cells independently from MHC recognition. NK cells are modulated …

Ovarian cancer is one of the most lethal female cancers. For accurate prognosis prediction,
this study aimed to investigate novel, blood-based prognostic biomarkers for high-grade …

CD24 has emerged as a molecule of significant interest beyond the oncological arena.
Recent studies have unveiled its surprising and diverse roles in various biological …

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies and is
currently the third leading cause of cancer death. The aggressiveness of PDAC stems from …

Simple Summary Tumor cells accumulate sialylation in tissues via the coordination of
sialyltransferases and sialidases. Tumor sialylation can block receptor and ligand binding at …