Metabolomics for investigating physiological and pathophysiological processes
DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
Homocysteine metabolism as the target for predictive medical approach, disease prevention, prognosis, and treatments tailored to the person
L Koklesova, A Mazurakova, M Samec, K Biringer… - EPMA Journal, 2021 - Springer
Homocysteine (Hcy) metabolism is crucial for regulating methionine availability, protein
homeostasis, and DNA-methylation presenting, therefore, key pathways in post-genomic …
homeostasis, and DNA-methylation presenting, therefore, key pathways in post-genomic …
The controversial role of homocysteine in neurology: from labs to clinical practice
R Moretti, P Caruso - International journal of molecular sciences, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing amino acid that is generated during methionine
metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin …
metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin …
Diagnostic, prognostic, and mechanistic biomarkers of diabetes mellitus-associated cognitive decline
H Ehtewish, A Arredouani, O El-Agnaf - International journal of molecular …, 2022 - mdpi.com
Cognitive dysfunctions such as mild cognitive impairment (MCI), Alzheimer's disease (AD),
and other forms of dementia are recognized as common comorbidities of type 2 diabetes …
and other forms of dementia are recognized as common comorbidities of type 2 diabetes …
Neuroprotective strategies for neurological disorders by natural products: an update
Nature has bestowed mankind with surplus resources (natural products) on land and water.
Natural products have a significant role in the prevention of disease and boosting of health …
Natural products have a significant role in the prevention of disease and boosting of health …
Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease
KG Goozee, TM Shah, HR Sohrabi… - British Journal of …, 2016 - cambridge.org
Curcumin derived from turmeric is well documented for its anti-carcinogenic, antioxidant and
anti-inflammatory properties. Recent studies show that curcumin also possesses …
anti-inflammatory properties. Recent studies show that curcumin also possesses …
Epilepsy is a neurological and a systemic disorder
The basic pathophysiology of epilepsy is still not fully understood. Epidemiological evidence
for epilepsy seems to suggest that it may not only be the propensity for seizures to occur …
for epilepsy seems to suggest that it may not only be the propensity for seizures to occur …
Reductive metabolites of curcumin and their therapeutic effects
Curcumin, a secondary metabolite from the turmeric plant is one of the most promising
natural products, which has been studied extensively for decades. It has demonstrated …
natural products, which has been studied extensively for decades. It has demonstrated …
[HTML][HTML] p38 MAPK and PI3K/AKT signalling cascades inParkinson's disease
SK Jha, NK Jha, R Kar, RK Ambasta… - International journal of …, 2015 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a chronic neurodegenerative condition which has the second
largest incidence rate among all other neurodegenerative disorders barring Alzheimer's …
largest incidence rate among all other neurodegenerative disorders barring Alzheimer's …
Targeting T-type/CaV3. 2 channels for chronic pain
T-type calcium channels regulate neuronal excitability and are important contributors of pain
processing. CaV3. 2 channels are the major isoform expressed in nonpeptidergic and …
processing. CaV3. 2 channels are the major isoform expressed in nonpeptidergic and …