Polycystic ovary syndrome: etiology, current management, and future therapeutics
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder, typically
characterized by anovulation, infertility, obesity, insulin resistance, and polycystic ovaries …
characterized by anovulation, infertility, obesity, insulin resistance, and polycystic ovaries …
Essential role of granulosa cell glucose and lipid metabolism on oocytes and the potential metabolic imbalance in polycystic ovary syndrome
CH Zhang, XY Liu, J Wang - International journal of molecular sciences, 2023 - mdpi.com
Granulosa cells are crucial for the establishment and maintenance of bidirectional
communication among oocytes. Various intercellular material exchange modes, including …
communication among oocytes. Various intercellular material exchange modes, including …
Genetic and Epigenetic Landscape for Drug Development in Polycystic Ovary Syndrome
Y Chen, G Wang, J Chen, C Wang, X Dong… - Endocrine …, 2024 - academic.oup.com
The treatment of polycystic ovary syndrome (PCOS) faces challenges as all known
treatments are merely symptomatic. The US Food and Drug Administration (FDA) has not …
treatments are merely symptomatic. The US Food and Drug Administration (FDA) has not …
Circulating miRNAs in women with polycystic ovary syndrome: a longitudinal cohort study
PB Udesen, AE Sørensen, R Svendsen, NLS Frisk… - Cells, 2023 - mdpi.com
Background: Women with polycystic ovary syndrome (PCOS) often change their metabolic
profile over time to decrease levels of androgens while often gaining a propensity for the …
profile over time to decrease levels of androgens while often gaining a propensity for the …
Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity and treatment with metformin and GLP-1s
A Etrusco, M Mikuš, A D'Amato, F Barra, P Planinić… - Biomedicines, 2024 - mdpi.com
Background: The purpose of this narrative review is to describe the mechanisms that are
responsible for the development of infertility and PCOS, with a focus on the role of obesity …
responsible for the development of infertility and PCOS, with a focus on the role of obesity …
The role of MicroRNA, long non-coding RNA and circular RNA in the pathogenesis of polycystic ovary syndrome: A literature review
JS Nasser, N Altahoo, S Almosawi, A Alhermi… - International journal of …, 2024 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine-metabolic disease in
females of reproductive age, affecting 4–20% of pre-menopausal women worldwide …
females of reproductive age, affecting 4–20% of pre-menopausal women worldwide …
Kisspeptin regulates the proliferation and apoptosis of ovary granulosa cells in polycystic ovary syndrome by modulating the PI3K/AKT/ERK signalling pathway
P Sun, Y Zhang, L Sun, N Sun, J Wang, H Ma - BMC Women's Health, 2023 - Springer
Background The development of polycystic ovary syndrome (PCOS) is closely correlated
with apoptosis and oxidative stress in ovarian granulosa cells. Kisspeptin plays an important …
with apoptosis and oxidative stress in ovarian granulosa cells. Kisspeptin plays an important …
Circulating miRNAs and preeclampsia: from implantation to epigenetics
SR Giannubilo, M Cecati, D Marzioni… - International Journal of …, 2024 - mdpi.com
In this review, we comprehensively present the literature on circulating microRNAs
(miRNAs) associated with preeclampsia, a pregnancy-specific disease considered the …
(miRNAs) associated with preeclampsia, a pregnancy-specific disease considered the …
Biomarkers in polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-
age women. PCOS is diagnosed by the presence of two of the following three …
age women. PCOS is diagnosed by the presence of two of the following three …
miRNA expression in PCOS: Unveiling a paradigm shift toward biomarker discovery
G Rashid, NA Khan, D Elsori, RA Youness… - Archives of Gynecology …, 2024 - Springer
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects a substantial
percentage of women, estimated at around 9–21%. This condition can lead to anovulatory …
percentage of women, estimated at around 9–21%. This condition can lead to anovulatory …