[HTML][HTML] Animal and organoid models of liver fibrosis

Y Bao, L Wang, H Pan, T Zhang, Y Chen, S Xu… - Frontiers in …, 2021 - frontiersin.org
Liver fibrosis refers to the process underlying the development of chronic liver diseases,
wherein liver cells are repeatedly destroyed and regenerated, which leads to an excessive …

Discovery of the first ataxia telangiectasia and Rad3-related (ATR) degraders for cancer treatment

L Huang, J Shao, W Lai, H Gu, J Yang, S Shi… - European Journal of …, 2024 - Elsevier
The first examples of ataxia telangiectasia and Rad3-related (ATR) PROTACs were
designed and synthesized. Among them, the most potent degrader, ZS-7, demonstrated …

Differential Proteomic Analysis of Dimethylnitrosamine (DMN)‐Induced Liver Fibrosis

X Liu, R Dai, M Ke, I Suheryani, W Meng, Y Deng - Proteomics, 2017 - Wiley Online Library
Liver fibrosis is a common pathological feature of many chronic liver diseases. To
characterize the entire panorama of proteome changes in dimethylnitrosamine (DMN) …

肝纤维化无创诊断的研究进展

杨二娜, 曹武奎 - 临床肝胆病杂志, 2017 - lcgdbzz.org
肝纤维化是多种慢性肝病共同的病理学基础, 肝活组织检查作为目前评估和诊断肝纤维化的金
标准, 因其有创性和操作的高要求大大限制了其临床应用. 介绍了近年来肝纤维化无创诊断在 …

[HTML][HTML] EPA plus DHA improves survival related to a decrease of injury after extended liver ischemia in Sprague-Dawley rats

N Céspedes, A Tamayo, MJ Rodriguez… - Annals of …, 2020 - Elsevier
Introduction and objectives The omega-3 fatty acids (ω3), EPA and DHA, have been
described for their beneficial effects on metabolism and inflammation. In addition, they are …

Pharmacologically Induced Animal Models for Various Diseases

S Ramesh, L Kalaiselvi, MR Srinivasan - Animal Models in Research …, 2024 - Springer
Despite the advances in genetics and genetic models, drug-induced models of animal
disease are still popular for the ease of model development. Over the years, these models …

[PDF][PDF] Dynamic relationship between SIPA1 gene and protein expression and the development of gastric cancer

JY Li, JB Wang, CB Liu, DL Ma, JH Ma - Genet Mol Res, 2017 - funpecrp.com.br
Association of signal-induced proliferation-associated 1 (SIPA) gene and protein expression
with gastric cancer development was examined. SIPA1 mRNA and protein levels were …

Research advances in noninvasive diagnosis of hepatic fibrosis

Y ErNa, C WuKui - 临床肝胆病杂志, 2017 - lcgdbzz.org
Hepatic fibrosis is the common pathological basis of various chronic liver diseases. Liver
biopsy remains the gold standard for the assessment and diagnosis of liver fibrosis, but its …