Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the
adult population. OA is primarily caused by trauma induced by an external force or by age …

Pathological calcification of cartilage is a hallmark of osteoarthritis (OA). Calcification can be
observed both at the cartilage surface and in its deeper layers. The formation of calcium …

OBJECTIVE: To review the literature on the role and regulation of chondrocyte terminal
differentiation (hypertrophy-like changes) in osteoarthritis (OA) and to integrate this in a …

Articular cartilage repair and regeneration provides a substantial challenge in Regenerative
Medicine because of the high degree of morphological and mechanical complexity intrinsic …

Osteoarthritis (OA) is a common joint degenerative disease affecting the whole joint
structure, including articular cartilage, subchondral bone and synovial tissue. Although …

The cellular and molecular mechanisms responsible for the initiation and progression of
osteoarthritis (OA), and in particular cartilage degeneration in OA, are not completely …

Introduction Recent findings suggest that articular cartilage contains mesenchymal
progenitor cells. The aim of this study was to examine the distribution of stem cell markers …

The formation of new cell clusters is a histological hallmark of arthritic cartilage but the
biology of clusters and their role in disease are poorly understood. This is the first …

Objective By producing instability in mouse knee joints, we attempted to determine the
involvement of runt‐related transcription factor 2 (RUNX‐2), which is required for …

Osteoarthritis is a degenerative disease and frequently involves the knee, hip and
phalangeal joints. Current treatments used in small cartilage defects including multiple …