Ten years of EWAS
S Wei, J Tao, J Xu, X Chen, Z Wang, N Zhang… - Advanced …, 2021 - Wiley Online Library
Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation
variation in complex diseases for a decade, and epigenome as a research target has …
variation in complex diseases for a decade, and epigenome as a research target has …
[HTML][HTML] Computational challenges in detection of cancer using cell-free DNA methylation
Cell-free DNA (cfDNA) methylation profiling is considered promising and potentially reliable
for liquid biopsy to study progress of diseases and develop reliable and consistent …
for liquid biopsy to study progress of diseases and develop reliable and consistent …
DNA methylation changes in the sperm of captive-reared fish: a route to epigenetic introgression in wild populations
D Rodriguez Barreto, C Garcia de Leaniz… - Molecular Biology …, 2019 - academic.oup.com
Interbreeding between hatchery-reared and wild fish, through deliberate stocking or
escapes from fish farms, can result in rapid phenotypic and gene expression changes in …
escapes from fish farms, can result in rapid phenotypic and gene expression changes in …
A three‐gene DNA methylation biomarker accurately classifies early stage prostate cancer
PG Patel, T Wessel, A Kawashima, JBA Okello… - The …, 2019 - Wiley Online Library
Background We identify and validate accurate diagnostic biomarkers for prostate cancer
through a systematic evaluation of DNA methylation alterations. Materials and methods We …
through a systematic evaluation of DNA methylation alterations. Materials and methods We …
Integrative mapping of the dog epigenome: Reference annotation for comparative intertissue and cross-species studies
Dogs have become a valuable model in exploring multifaceted diseases and biology
relevant to human health. Despite large-scale dog genome projects producing high-quality …
relevant to human health. Despite large-scale dog genome projects producing high-quality …
Interplay between maternal Slc6a4 mutation and prenatal stress: a possible mechanism for autistic behavior development
The low activity allele of the maternal polymorphism, 5HTTLPR, in the serotonin transporter,
SLC6A4, coupled with prenatal stress is reported to increase the risk for children to develop …
SLC6A4, coupled with prenatal stress is reported to increase the risk for children to develop …
Goldmine integrates information placing genomic ranges into meaningful biological contexts
JM Bhasin, AH Ting - Nucleic acids research, 2016 - academic.oup.com
Bioinformatic analysis often produces large sets of genomic ranges that can be difficult to
interpret in the absence of genomic context. Goldmine annotates genomic ranges from any …
interpret in the absence of genomic context. Goldmine annotates genomic ranges from any …
Epigenetic targeting of adipocytes inhibits high-grade serous ovarian cancer cell migration and invasion
J Tang, N Pulliam, A Özeş, A Buechlein, N Ding… - Molecular Cancer …, 2018 - AACR
Ovarian cancer (OC) cells frequently metastasize to the omentum, and adipocytes play a
significant role in ovarian tumor progression. Therapeutic interventions targeting aberrant …
significant role in ovarian tumor progression. Therapeutic interventions targeting aberrant …
[HTML][HTML] Data showing atherosclerosis-associated differentially methylated regions are often at enhancers
Atherosclerosis involves phenotypic modulation and transdifferentiation of vascular smooth
muscle cells (SMCs). Data are given in tabular or figure format that illustrate genome-wide …
muscle cells (SMCs). Data are given in tabular or figure format that illustrate genome-wide …
Whole-genome differentially hydroxymethylated DNA regions among twins discordant for cardiovascular death
J Dai, M Leung, W Guan, HT Guo, RE Krasnow… - Genes, 2021 - mdpi.com
Epigenetics is a mechanism underlying cardiovascular disease. It is unknown whether DNA
hydroxymethylation is prospectively associated with the risk for cardiovascular death …
hydroxymethylation is prospectively associated with the risk for cardiovascular death …