Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications

BR Stockwell - Cell, 2022 - cell.com
Ferroptosis, a form of cell death driven by iron-dependent lipid peroxidation, was identified
as a distinct phenomenon and named a decade ago. Ferroptosis has been implicated in a …

From natural environment to animal tissues: A review of microplastics (nanoplastics) translocation and hazards studies

X Dong, X Liu, Q Hou, Z Wang - Science of the Total Environment, 2023 - Elsevier
Abstract Microplastics (MPs) and nanoplastic (NPs) pollution is a global concern due to the
massive use of plastic products. Although there have been many studies on the treatments …

The emerging role of microplastics in systemic toxicity: Involvement of reactive oxygen species (ROS)

A Das - Science of The Total Environment, 2023 - Elsevier
Plastic pollution is one of the most pressing environmental threats the world is facing
currently. The degradation of macroplastics into smaller forms viz. microplastics (MPs) or …

[HTML][HTML] A review of potential human health impacts of micro-and nanoplastics exposure

JL Xu, X Lin, JJ Wang, AA Gowen - Science of the Total Environment, 2022 - Elsevier
This systematic review aims to summarize the current knowledge on biological effects of
micro-and nanoplastics (MNPs) on human health based on mammalian systems. An …

Polystyrene microplastics up-regulates liver glutamine and glutamate synthesis and promotes autophagy-dependent ferroptosis and apoptosis in the cerebellum …

K Yin, D Wang, H Zhao, Y Wang, Y Zhang, Y Liu… - Environmental …, 2022 - Elsevier
Microplastics (MPs), which are emerging environmental pollutants, remain uncertainties in
their toxic mechanism. MPs have been linked to severe liver metabolic disorders and …

Effects of polystyrene microplastics on human kidney and liver cell morphology, cellular proliferation, and metabolism

KE Goodman, T Hua, QXA Sang - ACS omega, 2022 - ACS Publications
Microplastics have gained much attention due to their prevalence and abundance in our
everyday lives. They have been detected in household items such as sugar, salt, honey …

[HTML][HTML] 4-tert-butylphenol triggers common carp hepatocytes ferroptosis via oxidative stress, iron overload, SLC7A11/GSH/GPX4 axis, and ATF4/HSPA5/GPX4 axis

J Cui, Q Zhou, M Yu, Y Liu, X Teng, X Gu - … and Environmental Safety, 2022 - Elsevier
tert-butylphenol (4-tBP) is a toxic environmental pollutant with moderate bioaccumulation,
environmental persistence, and long-term toxicity. Its toxicity to aquatic organisms has …

Microplastics induced inflammation and apoptosis via ferroptosis and the NF-κB pathway in carp

T Xu, J Cui, R Xu, J Cao, M Guo - Aquatic Toxicology, 2023 - Elsevier
Microplastics (MPs), a new class of pollutant that threatens aquatic biodiversity, are
becoming increasingly prevalent around the world. Fish growth may be severely inhibited by …

The potential impacts of micro-and-nano plastics on various organ systems in humans

N Ali, J Katsouli, EL Marczylo, TW Gant, S Wright… - …, 2024 - thelancet.com
Humans are exposed to micro-and-nano plastics (MNPs) through various routes, but the
adverse health effects of MNPs on different organ systems are not yet fully understood. This …

Food and human safety: The impact of microplastics

K Kadac-Czapska, E Knez… - Critical Reviews in Food …, 2024 - Taylor & Francis
Plastic waste pollution is one of the biggest problems in the world today. The amount of
plastic in the environment continues to increase, and human exposure to microplastic (MP) …