[HTML][HTML] Frequency and mortality of septic shock in Europe and North America: a systematic review and meta-analysis

JL Vincent, G Jones, S David, E Olariu, KK Cadwell - Critical care, 2019 - Springer
Background Septic shock is the most severe form of sepsis, in which profound underlying
abnormalities in circulatory and cellular/metabolic parameters lead to substantially …

Sepsis: pathophysiology and clinical management

JE Gotts, MA Matthay - Bmj, 2016 - bmj.com
Sepsis, severe sepsis, and septic shock represent increasingly severe systemic
inflammatory responses to infection. Sepsis is common in the aging population, and it …

Sex and gender differences in bacterial infections

SP Dias, MC Brouwer, D van de Beek - Infection and Immunity, 2022 - Am Soc Microbiol
There is a growing awareness of the importance of sex and gender in medicine and
research. Women typically have stronger immune responses to self and foreign antigens …

Epidemiology of severe sepsis

FB Mayr, S Yende, DC Angus - Virulence, 2014 - Taylor & Francis
Severe sepsis is a leading cause of death in the United States and the most common cause
of death among critically ill patients in non-coronary intensive care units (ICU). Respiratory …

[HTML][HTML] The impact of estrogens and their receptors on immunity and inflammation during infection

AT Harding, NS Heaton - Cancers, 2022 - mdpi.com
Simple Summary Human health is significantly affected by microbial infections. One of the
largest determinants of the outcomes of such infections is the host immune response. Too …

[HTML][HTML] Gender differences in trauma, shock and sepsis

F Bösch, MK Angele, IH Chaudry - Military Medical Research, 2018 - Springer
Despite efforts in prevention and intensive care, trauma and subsequent sepsis are still
associated with a high mortality rate. Traumatic injury remains the main cause of death in …

[HTML][HTML] Interactions between gender and sepsis—implications for the future

I Lakbar, S Einav, N Lalevée, I Martin-Loeches… - Microorganisms, 2023 - mdpi.com
Sex and gender dimorphisms are found in a large variety of diseases, including sepsis and
septic shock which are more prevalent in men than in women. Animal models show that the …

Current trends in sepsis-related mortality in the United States

J Prest, M Sathananthan, N Jeganathan - Critical care medicine, 2021 - journals.lww.com
OBJECTIVES: Sepsis is a life-threatening condition and is one of the leading causes of
death in the United States. The burden of sepsis-related mortality in the United States in …

[HTML][HTML] Analysis of volatile organic compounds in exhaled breath to diagnose ventilator-associated pneumonia

R Schnabel, R Fijten, A Smolinska, J Dallinga… - Scientific reports, 2015 - nature.com
Ventilator-associated pneumonia (VAP) is a nosocomial infection occurring in the intensive
care unit (ICU). The diagnostic standard is based on clinical criteria and bronchoalveolar …

Comparison of 5% human albumin and normal saline for fluid resuscitation in sepsis induced hypotension among patients with cirrhosis (FRISC study): a randomized …

CA Philips, R Maiwall, MK Sharma, A Jindal… - Hepatology …, 2021 - Springer
Aims Sepsis and septic shock are common causes of hospitalization and mortality in
patients with cirrhosis. There is no data on the choice of fluid and resuscitation protocols in …