Impact of non-invasive biomarkers on hepatology practice: past, present and future

QM Anstee, L Castera, R Loomba - Journal of hepatology, 2022 - Elsevier
Over the last two decades, there have been tremendous advances in the non-invasive
diagnosis and risk stratification of chronic liver diseases (CLDs). Non-invasive approaches …

Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

Association of direct-acting antiviral therapy with liver and nonliver complications and long-term mortality in patients with chronic hepatitis C

E Ogawa, N Chien, L Kam, YH Yeo, F Ji… - JAMA Internal …, 2023 - jamanetwork.com
Importance Chronic hepatitis C (CHC) and its complications are associated with high rates
of morbidity and mortality. However, large-scale data analysis of the long-term liver and …

[HTML][HTML] The Baveno VII concept of cirrhosis recompensation

T Reiberger, BS Hofer - Digestive and Liver Disease, 2023 - Elsevier
Traditionally, the progression from compensated to decompensated cirrhosis has been
regarded as a point of no return in the natural history of the disease. However, this point of …

[HTML][HTML] A new clinical and prognostic characterization of the patterns of decompensation of cirrhosis

M Tonon, R D'Ambrosio, V Calvino, G Tosetti… - Journal of …, 2024 - Elsevier
Background & Aims The prognostic impact of acute decompensation (AD), ie the
development of complications that require hospitalization, has recently been assessed …

Mortality rates among patients successfully treated for hepatitis C in the era of interferon-free antivirals: population based cohort study

V Hamill, S Wong, J Benselin, M Krajden, PC Hayes… - bmj, 2023 - bmj.com
Objectives To quantify mortality rates for patients successfully treated for hepatitis C in the
era of interferon-free, direct acting antivirals and compare these rates with those of the …

Indolent cancer and pattern of progression: Two missing parameters in trial design for hepatology

M Iavarone, JC Nault, G Cabibbo, F Torres, M Reig - Hepatology, 2024 - journals.lww.com
The indolent and aggressive behaviors of HCC might have a role in clinical trial (CT) results;
however, the indolent HCC is less analyzed compared to others cancer. Indolent profile …

Etiological cure prevents further decompensation and mortality in patients with cirrhosis with ascites as the single first decompensating event

M Tonon, L Balcar, G Semmler, V Calvino… - Hepatology, 2023 - journals.lww.com
Etiological cure prevents further decompensation and mortali... : Hepatology Etiological cure
prevents further decompensation and mortality in patients with cirrhosis with ascites as the single …

Long-term hepatocellular carcinoma development and predictive ability of non-invasive scoring systems in patients with HCV-related cirrhosis treated with direct …

GP Caviglia, G Troshina, U Santaniello, G Rosati… - Cancers, 2022 - mdpi.com
Simple Summary In the present study we investigated the ability of different non-invasive
scoring systems (ie, Forns index, APRI, FIB-4, ALBI, and aMAP) to predict hepatocellular …

Chronic hepatitis C: advances in therapy and the remaining challenges

SA Alqahtani, MS Sulkowski - Medical Clinics, 2023 - medical.theclinics.com
It is estimated that 58 million people suffer from chronic hepatitis C virus (HCV) infection
worldwide, which significantly contributes to chronic liver disease and liverrelated mortality …