[HTML][HTML] Optic neuritis in multiple sclerosis—a review of molecular mechanisms involved in the degenerative process

MA Ciapă, DL Șalaru, C Stătescu, RA Sascău… - Current Issues in …, 2022 - mdpi.com
Multiple sclerosis is a central nervous system inflammatory demyelinating disease with a
wide range of clinical symptoms, ocular involvement being frequently marked by the …

[HTML][HTML] Non-traditional pro-inflammatory and pro-atherosclerotic risk factors related to systemic lupus erythematosus

P Richter, A Cardoneanu, C Rezus, AM Burlui… - International Journal of …, 2022 - mdpi.com
Cardiovascular diseases (CVD) are one of the leading causes of high mortality in patients
with systemic lupus erythematosus (SLE). The Framingham risk score and other traditional …

[HTML][HTML] Identification of diagnostic biomarkers and therapeutic targets in peripheral immune landscape from coronary artery disease

X Feng, Y Zhang, M Du, S Li, J Ding, J Wang… - Journal of Translational …, 2022 - Springer
Background Peripheral biomarkers are increasingly vital non-invasive methods for
monitoring coronary artery disease (CAD) progression. Their superiority in early detection …

[HTML][HTML] Network pharmacology- and molecular docking-based analyses of the antihypertensive mechanism of Ilex kudingcha

F Liao, M Yousif, R Huang, Y Qiao, Y Hu - Frontiers in Endocrinology, 2023 - frontiersin.org
Herein, network pharmacology was used to identify the active components in Ilex kudingcha
and common hypertension-related targets. Gene Ontology (GO) and Kyoto Encyclopedia of …

[HTML][HTML] Epicardial adipose tissue thickness is related to plaque composition in coronary artery disease

SS Park, J Jung, GS Mintz, U Jin, JS Park, B Park… - Diagnostics, 2022 - mdpi.com
(1) Background: Currently, limited data are available regarding the relationship between
epicardial fat and plaque composition. The aim of this study was to assess the relationship …

[HTML][HTML] Immune-related potential biomarkers and therapeutic targets in coronary artery disease

C Liu, J Liu, Y Zhang, X Wang, Y Guan - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Background: Coronary artery disease (CAD) is a complex illness with unknown
pathophysiology. Peripheral biomarkers are a non-invasive method required to track the …

[HTML][HTML] Could a lipid oxidative biomarker be applied to improve risk stratification in the prevention of cardiovascular disease?

MVMB Pimentel, A Bertolami, LP Fernandes… - Biomedicine & …, 2023 - Elsevier
There is significant evidence demonstrating the influence of oxidative stress on
atherosclerosis and cardiovascular diseases (CVD). However, oxidative biomarkers have …

[HTML][HTML] Targeting inflammation in atherosclerosis: Overview, strategy and directions

R Waksman, I Merdler, BC Case… - …, 2024 - eurointervention.pcronline.com
Atherosclerosis is a chronic condition characterised by the build-up of plaque in the inner
lining of the blood vessels and it is the main underlying cause of cardiovascular disease …

[HTML][HTML] Coronary artery disease patient-derived iPSC-hepatocytes have distinct miRNA profile that may alter lipid metabolism

A Alexanova, E Raitoharju, J Valtonen… - Scientific Reports, 2023 - nature.com
Metabolic dysfunction, partly driven by altered liver function, predisposes to coronary artery
disease (CAD), but the role of liver in vulnerable atherosclerotic plaque development …

[HTML][HTML] Cytokines in Systemic Lupus Erythematosus—Focus on TNF-α and IL-17

P Richter, LA Macovei, IR Mihai, A Cardoneanu… - International Journal of …, 2023 - mdpi.com
Systemic lupus erythematosus (SLE) is an autoimmune disorder known for its complex
pathogenesis, in which cytokines play an essential role. It seems that the modulation of …