Drug compulsion manifests in some but not all individuals and implicates multifaceted
processes including failures in top‐down cognitive control as drivers for the hazardous …

Influential accounts of addiction posit alterations in adaptive behavior driven by deficient
dopaminergic prediction errors (PEs), signaling the discrepancy between actual and …

Individuals engage in the process of risk-based decision making on a daily basis to navigate
various aspects of life. There are, however, individual differences in this form of decision …

Compulsive drug intake is characterized by the continuation of use regardless of negative
consequences. This is modeled preclinically using procedures where a negative stimulus is …

Individuals who use cocaine exhibit maladaptive decision-making, overweighting rewards,
and underweighting potential risks. We previously showed that chronic cocaine self …

Introduction Motor impulsivity and risk-related impulsive choice have been proposed as
vulnerability factors for drug abuse, due to their high prevalence in drug abusers. However …

An overview of commonalities in the mechanisms underlying gambling and substance use
disorders Page 1 An overview of commonalities in the mechanisms underlying gambling …

Deficits in decision making are at the heart of many psychiatric diseases, such as substance
abuse disorders and attention deficit hyperactivity disorder. Consequently, rodent models of …

Navigating complex decisions and considering their relative risks and rewards is an
important cognitive ability necessary for survival. However, use of and dependence on illicit …

Addictions are characterized by choices made to satisfy the addiction despite the risk it could
produce an adverse consequence. Here, we developed a murine version of a 'risky decision …