Nanotechnology based drug delivery system: Current strategies and emerging therapeutic potential for medical science

T Sahu, YK Ratre, S Chauhan, L Bhaskar… - Journal of Drug Delivery …, 2021 - Elsevier
Nanotechnology or Nano medicine has been identified as the dominant and most
commercially invented technology that aims to improve the quality of health care strategies …

Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies

W Li, H Zhang, YG Assaraf, K Zhao, X Xu, J Xie… - Drug Resistance …, 2016 - Elsevier
Multidrug resistance is a key determinant of cancer chemotherapy failure. One of the major
causes of multidrug resistance is the enhanced efflux of drugs by membrane ABC …

Recent advances of metal-based nanoparticles in nucleic acid delivery for therapeutic applications

AR Sharma, YH Lee, A Bat-Ulzii… - Journal of …, 2022 - Springer
Recent efforts in designing nanomaterials to deliver potential therapeutics to the targeted
site are overwhelming and palpable. Engineering nanomaterials to deliver biological …

Recent advances in nanotechnology-based drug delivery systems for the kidney

F Oroojalian, F Charbgoo, M Hashemi, A Amani… - Journal of controlled …, 2020 - Elsevier
The application of nanotechnology in medicine has the potential to make a great impact on
human health, ranging from prevention to diagnosis and treatment of disease. The kidneys …

Polymeric nanoparticles for nasal drug delivery to the brain: relevance to Alzheimer's disease

N Rabiee, S Ahmadi, R Afshari, S Khalaji… - Advanced …, 2021 - Wiley Online Library
Currently, Alzheimer's disease (AD) accounts for more than half of all dementia cases.
Although genetics, age, and environmental factors affect the disease, the cause of AD is not …

Polymer nanoparticles mediated codelivery of antimiR-10b and antimiR-21 for achieving triple negative breast cancer therapy

R Devulapally, NM Sekar, TV Sekar, K Foygel… - ACS …, 2015 - ACS Publications
The current study shows the therapeutic outcome achieved in triple negative breast cancer
(TNBC) by simultaneously antagonizing miR-21-induced antiapoptosis and miR-10b …

Recent advances and prospects in gemcitabine drug delivery systems

S Paroha, J Verma, RD Dubey, RP Dewangan… - International Journal of …, 2021 - Elsevier
Cancer is a community health hazard which progress at a fatal rate in various countries
across the globe. An agent used for chemotherapy should exhibit ideal properties to be an …

[HTML][HTML] UTMD-promoted co-delivery of gemcitabine and miR-21 inhibitor by dendrimer-entrapped gold nanoparticles for pancreatic cancer therapy

L Lin, Y Fan, F Gao, L Jin, D Li, W Sun, F Li, P Qin… - Theranostics, 2018 - ncbi.nlm.nih.gov
Conventional chemotherapy of pancreatic cancer (PaCa) suffers the problems of low drug
permeability and inherent or acquired drug resistance. Development of new strategies for …

AS1411 aptamer-decorated cisplatin-loaded poly(lactic-co-glycolic acid) Nanoparticles for Targeted Therapy of miR-21-inhibited Ovarian Cancer Cells

S Vandghanooni, M Eskandani, J Barar, Y Omidi - Nanomedicine, 2018 - Taylor & Francis
Aim: The overexpression of miRNA-21 correlates with the cisplatin (CIS) resistance in the
ovarian cancers. Methods: AS1411 antinucleolin aptamer-decorated PEGylated poly (lactic …

Ultrasound-guided delivery of microRNA loaded nanoparticles into cancer

TY Wang, JW Choe, K Pu, R Devulapally… - Journal of Controlled …, 2015 - Elsevier
Ultrasound induced microbubble cavitation can cause enhanced permeability across natural
barriers of tumors such as vessel walls or cellular membranes, allowing for enhanced …