Complement activation has long been recognized as a central feature of membranous
nephropathy. Evidence for its role has been derived from the detection of complement …

Membranous nephropathy (MN) occurs predominantly in middle-aged and elderly
individuals and ranks among the most prevalent etiologies of elderly nephrotic syndrome. As …

The phospholipase A2 receptor 1 (PLA2R1) is the major target antigen in patients with
membranous nephropathy (MN), an antibody-mediated autoimmune glomerular disease …

Methods This study involved the design, generation, and characterization of CAAR cells
using NK-92 cells as well as primary human T cells. CAAR NK-92 cells and CAAR T cells …

Membranous nephropathy is a glomerulopathy, which main affected target is the podocyte,
and has consequences on the glomerular basement membrane. It is more common in …

Membranous nephropathy (MN) is an antibody-mediated autoimmune disease and the most
common cause of nephrotic syndrome in adults. The discovery of the phospholipase A2 …

Abstract The 14th International Podocyte Conference took place in Philadelphia, USA, from
May 23rd to 26th, 2023. It commenced with an early-career researchers' meeting on May …

Glomerulonephritis (GN) is a group of heterogeneous immune-mediated kidney diseases
that causes inflammation within the glomerulus. Autoantibodies (auto-Abs) are considered to …

The pathogenic role of anti-phospholipase A2 receptor (PLA2R) antibodies in primary
membranous nephropathy (MN) has been well-established. This study aimed to identify …

Background Primary membranous nephropathy (PMN) is an autoimmune kidney disease.
Despite the identification of certain autoantigens, etiology and pathophysiology of the PMN …