Background Drug development is currently hampered by high attrition rates; many
developed treatments fail during clinical testing. Part of the attrition may be due to low …

Systematic reviews are currently favored methods of evaluating research in order to reach
conclusions regarding medical practice. The need for such reviews is necessitated by the …

Philosophy of Economics: A Contemporary Introduction is the first systematic textbook in the
philosophy of economics. It introduces the epistemological, metaphysical and ethical …

Public acceptance of the use of animals in biomedical research is conditional on it
producing benefits for humans. Pandora Pound and Michael Bracken argue that the benefits …

We, the Editors and Publisher of the journal Current Medical Research and Opinion, have
retracted the following article: Mohamed Mediouni, Daniel R. Schlatterer, Henning Madry …

Background The requirement that animals be used in research and testing in order to protect
humans was formalized in the Nuremberg Code and subsequent national and international …

Animals can be used in many ways in science and scientific research. Given that society
values sentient animals and that basic research is not goal oriented, the question is raised:" …

We surveyed the scientific literature regarding amyotrophic lateral sclerosis, the SOD1
mouse model, complex adaptive systems, evolution, drug development, animal models, and …

The current use of animals to test for potential teratogenic effects of drugs and other
chemicals dates back to the thalidomide disaster of the late 1950s and early 1960s …

Every year, and in countries around the world, significant time and resources are devoted to
the noble cause of developing drugs to treat and cure human disease. With rare exception …