Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Osteoarthritis (OA) is a leading cause of disability worldwide and clinical pain is the major
symptom of OA. This clinical OA-related pain is firmly associated with symptoms of insomnia …

Pain, the primary symptom of osteoarthritis (OA), reduces both the quality and quantity of life
for patients. The pathophysiology of OA pain is complex and often difficult to explain solely …

The histone deacetylase inhibitor (HDACi) was a milestone in the treatment of refractory T-
cell lymphoma. However, the beneficial effects of HDACi have not been appreciated in …

Osteoarthritis (OA) is a common chronic degenerative joint disease in clinical practice with a
high prevalence, especially in the elderly. Traditional Chinese Medicine (TCM) believes that …

Osteoarthritis (OA), which is a major cause of serious arthralgia and disability among the
elderly, has long plagued numerous populations. However, the specific molecular …

Osteoarthritis (OA) is one of the most common degenerative diseases of articular cartilage.
During OA, all the elements that contribute to the joint undergo physiological and structural …

Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage injury,
hyperplasia of bone and inflammatory lesions of synovium. Monoacylglycerol lipase …

Ozone therapy (OT) is used for the treatment of multiple musculoskeletal disorders. In recent
years, there has been a growing interest in its use for the treatment of osteoarthritis (OA) …

Background: The most common cause of discomfort in old age is osteoarthritis. The age
range between 55 and 64 years old has the largest annual incidence of knee osteoarthritis …