Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation—Where Are We Now?

H Patil, SK Vemula, S Narala, P Lakkala… - AAPS …, 2024 - Springer
Hot-melt extrusion (HME) is a globally recognized, robust, effective technology that
enhances the bioavailability of poorly soluble active pharmaceutical ingredients and offers …

Development of a multi-component gastroretentive expandable drug delivery system (GREDDS) for personalized administration of metformin

M Uboldi, A Chiappa, M Rossi… - Expert Opinion on …, 2024 - Taylor & Francis
Objectives Efficacy and compliance of type II diabetes treatment would greatly benefit from
dosage forms providing controlled release of metformin in the upper gastrointestinal tract. In …

[HTML][HTML] Development of hybrid 3D-printed structure with aligned drug-loaded fibres using in-situ custom designed templates

K Muldoon, Y Feng, T Dooher, C O'Connor… - Journal of Drug Delivery …, 2023 - Elsevier
Fibre alignment technology is crucial in various emerging applications, such as drug
delivery systems, tissue engineering, and scaffold fabrication. However, conventional …

Liquid API feeding in pharmaceutical HME: Novel options in solid dosage manufacturing

L Kuchler, M Spoerk, S Eder, A Doğan, J Khinast… - International Journal of …, 2024 - Elsevier
Hot melt extrusion (HME) is a common unit operation. It is broadly applicable in the
pharmaceutical industry and can be implemented in a continuous manufacturing line …

Classification of Biomaterials and Surface Strategies

G Strohle, C Tan, H Li, AK Mohanty… - Surface Engineering of … - taylorfrancis.com
Significant research has been conducted to develop different types of biomaterials for
various applications. In this chapter, we will first introduce the classifications of biomaterials …