North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa …

A Alikhan, C Sayed, A Alavi, R Alhusayen… - Journal of the American …, 2019 - Elsevier
Hidradenitis suppurativa is a chronic inflammatory disorder affecting hair follicles, with
profoundly negative impact on patient quality of life. Evidence informing ideal evaluation and …

What causes hidradenitis suppurativa?—15 years after

CC Zouboulis, F Benhadou, AS Byrd… - Experimental …, 2020 - Wiley Online Library
The 14 authors of the first review article on hidradenitis suppurativa (HS) pathogenesis
published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st International …

Pyoderma gangrenosum: an update on pathophysiology, diagnosis and treatment

A Alavi, LE French, MD Davis, A Brassard… - American journal of …, 2017 - Springer
Pyoderma gangrenosum (PG) is a rare inflammatory neutrophilic disorder with prototypical
clinical presentations. Its pathophysiology is complex and not fully explained. Recent …

Adalimumab, ustekinumab, and secukinumab in the management of hidradenitis suppurativa: a review of the real-life experience

F Martora, M Megna, T Battista, L Potestio… - Clinical, Cosmetic …, 2023 - Taylor & Francis
To date, adalimumab (ADA) is the only biotechnology drug approved for the management of
hidradenitis suppurativa (HS), an inflammatory skin condition. However, it quickly became …

A comprehensive review of neutrophilic diseases

AV Marzano, A Borghi, D Wallach, M Cugno - Clinical reviews in allergy & …, 2018 - Springer
Neutrophilic dermatoses are a group of conditions characterized by the accumulation of
neutrophils in the skin and clinically presenting with polymorphic cutaneous lesions …

PAPA, PASH and PAPASH syndromes: pathophysiology, presentation and treatment

M Cugno, A Borghi, AV Marzano - American journal of clinical dermatology, 2017 - Springer
Pyoderma gangrenosum (PG) is a neutrophilic dermatosis usually manifesting as skin ulcers
with undermined erythematous-violaceous borders. It may be isolated, associated with …

Systemic associations of hidradenitis suppurativa

JJ Kohorst, AB Kimball, MDP Davis - Journal of the American Academy of …, 2015 - Elsevier
Hidradenitis suppurativa (HS) is a progressive, inflammatory disease that affects mostly
young women and appears to be caused by inflammation of hair follicles in areas of friction …

Potential of IL-1, IL-18 and inflammasome inhibition for the treatment of inflammatory skin diseases

G Fenini, E Contassot, LE French - Frontiers in pharmacology, 2017 - frontiersin.org
In 2002, intracellular protein complexes known as the inflammasomes were discovered and
were shown to have a crucial role in the sensing of intracellular pathogen-and danger …

Systematic review of immunomodulatory therapies for hidradenitis suppurativa

SYD Lim, HH Oon - Biologics: Targets and Therapy, 2019 - Taylor & Francis
Background: Greater understanding of the roles of tumor necrosis factor-α, IL-1β, IL-10, and
the IL-23/T-helper (Th) 17 and IL-12/Th1 pathways in immune dysregulation in …

PASH, PAPASH, PsAPASH, and PASS: The autoinflammatory syndromes of hidradenitis suppurativa

S Garcovich, G Genovese, C Moltrasio, D Malvaso… - Clinics in …, 2021 - Elsevier
Hidradenitis suppurativa (HS) is a chronic inflammatory disease usually involving the major
skin folds characterized by a multifactorial pathogenesis and a wide spectrum of clinical …