Understanding the Transcription Factor NFE2L1/NRF1 from the Perspective of Hallmarks of Cancer
H Zhang, Y Liu, K Zhang, Z Hong, Z Liu, Z Liu, G Li… - Antioxidants, 2024 - mdpi.com
Cancer cells subvert multiple properties of normal cells, including escaping strict cell cycle
regulation, gaining resistance to cell death, and remodeling the tumor microenvironment …
regulation, gaining resistance to cell death, and remodeling the tumor microenvironment …
Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy
MA Ward, JR Vangala, HE Kamber Kaya… - Journal of Cell …, 2024 - rupress.org
Cells exposed to proteotoxic stress invoke adaptive responses aimed at restoring
proteostasis. Our previous studies have established a firm role for the transcription factor …
proteostasis. Our previous studies have established a firm role for the transcription factor …
TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and-independent mechanisms without relying on heme and FBXO22
L Liu, M Matsumoto, M Watanabe-Matsui… - International Journal of …, 2024 - mdpi.com
BTB and CNC homology 1 (BACH1) represses the expression of genes involved in the
metabolism of iron, heme and reactive oxygen species. While BACH1 is rapidly degraded …
metabolism of iron, heme and reactive oxygen species. While BACH1 is rapidly degraded …