Chronic stress, drug use, and vulnerability to addiction

R Sinha - Annals of the new York Academy of Sciences, 2008 - Wiley Online Library
Stress is a well‐known risk factor in the development of addiction and in addiction relapse
vulnerability. A series of population‐based and epidemiological studies have identified …

The role of neuropeptide Y in cardiovascular health and disease

CMJ Tan, P Green, N Tapoulal… - Frontiers in …, 2018 - frontiersin.org
Neuropeptide Y (NPY) is an abundant sympathetic co-transmitter, widely found in the central
and peripheral nervous systems and with diverse roles in multiple physiological processes …

Role of neuropeptides in appetite regulation and obesity–a review

S Arora - Neuropeptides, 2006 - Elsevier
Obesity represents the most prevalent nutritional problem worldwide which in the long run
predisposes to development of diabetes mellitus, hypertension, endometrial carcinoma …

Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application

MJ Millan - Pharmacology & therapeutics, 2006 - Elsevier
Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

Central functions of neuropeptide Y in mood and anxiety disorders

G Wu, A Feder, G Wegener, C Bailey… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Neuropeptide Y (NPY) is a highly conserved neuropeptide belonging to the
pancreatic polypeptide family. Its potential role in the etiology and pathophysiology of mood …

In vitro selection of aptamers with affinity for neuropeptide Y using capillary electrophoresis

SD Mendonsa, MT Bowser - Journal of the American Chemical …, 2005 - ACS Publications
Capillary electrophoresis-systematic evolution of ligands by exponential enrichment (CE-
SELEX) was used to select aptamers for neuropeptide Y (NPY). This is the first example of a …

Neuropeptide Y (NPY) and posttraumatic stress disorder (PTSD): a translational update

SN Schmeltzer, JP Herman, R Sah - Experimental neurology, 2016 - Elsevier
Posttraumatic stress disorder (PTSD) is a trauma-evoked syndrome, with variable
prevalence within the human population due to individual differences in coping and …

Emotion processing, major depression, and functional genetic variation of neuropeptide Y

BJ Mickey, Z Zhou, MM Heitzeg, E Heinz… - Archives of general …, 2011 - jamanetwork.com
Context Despite recent progress in describing the common neural circuitry of emotion and
stress processing, the bases of individual variation are less well understood. Genetic …

Neuropeptide Y deficiency induces anxiety-like behaviours in zebrafish (Danio rerio)

K Shiozaki, M Kawabe, K Karasuyama, T Kurachi… - Scientific Reports, 2020 - nature.com
Neuropeptide Y (NPY) controls energy homeostasis including orexigenic actions in
mammalians and non-mammalians. Recently, NPY has attracted attention as a mediator of …

NPY receptors in human cancer: a review of current knowledge

M Körner, JC Reubi - Peptides, 2007 - Elsevier
Many peptide hormone receptors are over-expressed in human cancer, permitting an in vivo
targeting of tumors for diagnostic and therapeutic purposes. NPY receptors are novel and …