Hydrogen isotopes are unique tools for identifying and understanding biological and
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …

Moderately elevated plasma total homocysteine (tHcy) is a strong modifiable risk factor for
vascular dementia and Alzheimer's disease. Prospectively, elevated tHcy is associated with …

Phosphatidylserine (PS) is the major anionic phospholipid class particularly enriched in the
inner leaflet of the plasma membrane in neural tissues. PS is synthesized from …

Choline is an essential nutrient for humans. It is a precursor of membrane phospholipids (eg,
phosphatidylcholine (PC)), the neurotransmitter acetylcholine, and via betaine, the methyl …

Lung surfactant is a complex with a unique phospholipid and protein composition. Its
specific function is to reduce surface tension at the pulmonary air–liquid interface. The …

The N-terminal tails of eukaryotic histones are frequently posttranslationally modified. The
role of these modifications in transcriptional regulation is well-documented. However, the …

Lysophosphatidylcholine (LPC) and lysophosphatidic acid (LPA), the most prominent
lysoglycerophospholipids, are emerging as a novel class of inflammatory lipids, joining …

A randomized trial (VITACOG) in people with mild cognitive impairment (MCI) found that B
vitamin treatment to lower homocysteine slowed the rate of cognitive and clinical decline …

The aim of this review is to highlight current insights into the roles of choline and
docosahexaenoic acid (DHA) in maternal and infant nutrition, with special emphasis on …

Synapse loss and synaptic dysfunction are pathological processes already involved in the
early stages of Alzheimer's disease (AD). Synapses consist principally of neuronal …