Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Microbial transmission in the social microbiome and host health and disease

A Sarkar, CJA McInroy, S Harty, A Raulo, NGO Ibata… - Cell, 2024 - cell.com
Although social interactions are known to drive pathogen transmission, the contributions of
socially transmissible host-associated mutualists and commensals to host health and …

Resistant starch intake facilitates weight loss in humans by reshaping the gut microbiota

H Li, L Zhang, J Li, Q Wu, L Qian, J He, Y Ni… - Nature …, 2024 - nature.com
Emerging evidence suggests that modulation of gut microbiota by dietary fibre may offer
solutions for metabolic disorders. In a randomized placebo-controlled crossover design trial …

Digesting the complex metabolic effects of diet on the host and microbiome

RN Carmody, K Varady, PJ Turnbaugh - Cell, 2024 - cell.com
The past 50 years of interdisciplinary research in humans and model organisms has
delivered unprecedented insights into the mechanisms through which diet affects energy …

Adolescence and the microbiome: implications for healthy growth and maturation

MD Carson, C Westwater, CM Novince - The American Journal of …, 2023 - Elsevier
The gut microbiota was initially thought to develop into a stable, adult-like profile during
early postnatal life. The formation of the gut microbiota during early life has been shown to …

Gut microbial intersections with human ecology and evolution

KR Amato, RN Carmody - Annual Review of Anthropology, 2023 - annualreviews.org
Although microbiome science is relatively young, our knowledge of human-microbiome
interactions is growing rapidly and has already begun to transform our understanding of …

The potential of short-chain fatty acid epigenetic regulation in chronic low-grade inflammation and obesity

J Kopczyńska, M Kowalczyk - Frontiers in Immunology, 2024 - frontiersin.org
Obesity and chronic low-grade inflammation, often occurring together, significantly
contribute to severe metabolic and inflammatory conditions like type 2 diabetes (T2D) …

Acupuncture as multi-targeted therapy for the multifactorial disease obesity: a complex neuro-endocrine-immune interplay

RG Landgraaf, MN Bloem, M Fumagalli… - Frontiers in …, 2023 - frontiersin.org
The prevalence of obesity has reached pandemic dimensions. It is associated with multiple
comorbidities and is becoming a clinical and public health threat. Obesity is a multifactorial …

Weight loss promotion in individuals with obesity through gut microbiota alterations with a multiphase modified ketogenic diet

H Wang, X Lv, S Zhao, W Yuan, Q Zhou, FA Sadiq… - Nutrients, 2023 - mdpi.com
The occurrence of obesity and related metabolic disorders is rising, necessitating effective
long-term weight management strategies. With growing interest in the potential role of gut …

Practical strategies to manage obesity in type 2 diabetes

HW Rodbard, K Barnard‐Kelly… - Diabetes, Obesity …, 2024 - Wiley Online Library
The rising phenomenon of obesity, a major risk factor for the development and progression
of type 2 diabetes, is a complex and multifaceted issue that requires a comprehensive and …