Noninvasive cell-tracking methods

MF Kircher, SS Gambhir, J Grimm - Nature reviews Clinical oncology, 2011 - nature.com
Cell-based therapies, such as adoptive immunotherapy and stem-cell therapy, have
received considerable attention as novel therapeutics in oncological research and clinical …

Microcapsules and microcarriers for in situ cell delivery

RM Hernández, G Orive, A Murua, JL Pedraz - Advanced drug delivery …, 2010 - Elsevier
In recent years, the use of transplanted living cells pumping out active factors directly at the
site has proven to be an emergent technology. However a recurring impediment to rapid …

Lentiviral vectors as tools to understand central nervous system biology in mammalian model organisms

LC Parr-Brownlie, C Bosch-Bouju… - Frontiers in molecular …, 2015 - frontiersin.org
Lentiviruses have been extensively used as gene delivery vectors since the mid-1990s.
Usually derived from the human immunodeficiency virus genome, they mediate efficient …

Living cell factories‐electrosprayed microcapsules and microcarriers for minimally invasive delivery

SM Naqvi, S Vedicherla, J Gansau… - Advanced …, 2016 - Wiley Online Library
Minimally invasive delivery of “living cell factories” consisting of cells and therapeutic agents
has gained wide attention for next generation biomaterial device systems for multiple …

[HTML][HTML] Radionuclide-based molecular imaging allows CAR-T cellular visualization and therapeutic monitoring

F Shao, Y Long, H Ji, D Jiang, P Lei, X Lan - Theranostics, 2021 - ncbi.nlm.nih.gov
Chimeric antigen receptor T cell (CAR-T) therapy is a new and effective form of adoptive cell
therapy that is rapidly entering the mainstream for the treatment of CD19-positive …

Advances in CAR T cell therapy for non-small cell lung cancer

HY Ma, J Das, C Prendergast, D De Jong… - Current Issues in …, 2023 - mdpi.com
Since its first approval by the FDA in 2017, tremendous progress has been made in chimeric
antigen receptor (CAR) T cell therapy, the adoptive transfer of engineered, CAR-expressing …

Stem cell tracking technologies for neurological regenerative medicine purposes

Y Zheng, J Huang, T Zhu, R Li, Z Wang… - Stem cells …, 2017 - Wiley Online Library
The growing field of stem cell therapy is moving toward clinical trials in a variety of
applications, particularly for neurological diseases. However, this translation of cell …

Therapeutic cell encapsulation: ten steps towards clinical translation

E Santos, JL Pedraz, RM Hernández, G Orive - Journal of Controlled …, 2013 - Elsevier
Since the conception of cell microencapsulation, many scientists bet on this biotechnology
as they saw in it a promising alternative to protect transplanted cells from host …

[HTML][HTML] Multimodality reporter gene imaging: Construction strategies and application

M Li, Y Wang, M Liu, X Lan - Theranostics, 2018 - ncbi.nlm.nih.gov
Molecular imaging has played an important role in the noninvasive exploration of multiple
biological processes. Reporter gene imaging is a key part of molecular imaging. By …

Bacterial vectors for imaging and cancer gene therapy: a review

M Cronin, RM Stanton, KP Francis, M Tangney - Cancer gene therapy, 2012 - nature.com
The significant burden of resistance to conventional anticancer treatments in patients with
advanced disease has prompted the need to explore alternative therapeutic strategies. The …