Traumatic brain injury (TBI) is a leading cause of mortality and morbidity worldwide.
Neuroinflammation is prominent in the short and long-term consequences of neuronal …

Swelling of the brain or spinal cord (CNS edema) affects millions of people every year. All
potential pharmacological interventions have failed in clinical trials, meaning that symptom …

Traumatic brain injury (TBI), a major global health and socioeconomic problem, is now
established as a chronic disease process with a broad spectrum of pathophysiological …

Over 700 drugs have failed in stroke clinical trials, an unprecedented rate thought to be
attributed in part to limited and isolated testing often solely in “young” rodent models and …

Traumatic brain injury (TBI), a brain dysfunction for which there is no present effective
treatment, is often caused by a concussive impact to the head and affects an estimated 1.7 …

Organelle damage and increases in mitochondrial permeabilization are key events in the
development of cerebral ischemic tissue injury because they cause both modifications in …

Lewy body disease (LBD) is a neurodegenerative disease resulting in dementia. It shares
clinical and pathological features with Parkinson disease (PD), the most frequent …

Stroke induces tissue death both at the site of infarction and at secondary sites connected to
the primary infarction. This latter process has been referred to as secondary …

There is emerging evidence suggesting that a cortical stroke can cause delayed and remote
hippocampal dysregulation, leading to cognitive impairment. In this study, we aimed to …

Background Effects of air pollution on neurotoxicity and behavioral alterations have been
reported. The objective of this study was to investigate the pathophysiology caused by …