Regeneration of actin filament branches from the same Arp2/3 complex
F Ghasemi, LY Cao, M Mladenov, B Guichard… - Science …, 2024 - science.org
Branched actin filaments are found in many key cellular structures. Branches are nucleated
by the Arp2/3 complex activated by nucleation-promoting factor (NPF) proteins and bound to …
by the Arp2/3 complex activated by nucleation-promoting factor (NPF) proteins and bound to …
Liquid-like condensates mediate competition between actin branching and bundling
K Graham, A Chandrasekaran… - Proceedings of the …, 2024 - National Acad Sciences
Cellular remodeling of actin networks underlies cell motility during key morphological
events, from embryogenesis to metastasis. In these transformations, there is an inherent …
events, from embryogenesis to metastasis. In these transformations, there is an inherent …
[HTML][HTML] Direct observation of cortactin protecting Arp2/3-actin filament branch junctions from GMF-mediated destabilization
ER McGuirk, N Koundinya, P Nagarajan… - European journal of cell …, 2024 - Elsevier
How cells tightly control the formation and turnover of branched actin filament arrays to drive
cell motility, endocytosis, and other cellular processes is still not well understood. Here, we …
cell motility, endocytosis, and other cellular processes is still not well understood. Here, we …
[HTML][HTML] Both Las17-binding sites on Arp2/3 complex are important for branching nucleation and assembly of functional endocytic actin networks in S. cerevisiae
HY Narvaez-Ortiz, MJ Lynch, SL Liu, A Fries… - Journal of Biological …, 2024 - ASBMB
Arp2/3 complex nucleates branched actin filaments that drive membrane invagination during
endocytosis and leading-edge protrusion in lamellipodia. Arp2/3 complex is maximally …
endocytosis and leading-edge protrusion in lamellipodia. Arp2/3 complex is maximally …