Integration of genomic technology into healthcare settings establishes new capabilities to
predict disease susceptibility and optimize treatment regimes. Yet, Indigenous peoples …

The use of population descriptors such as race, ethnicity, and ancestry in science, medicine,
and public health has a long, complicated, and at times dark history, particularly for genetics …

In 2004, the Havasupai Tribe filed a lawsuit against the Arizona Board of Regents and
Arizona State University (ASU) researchers upon discovering their DNA samples, initially …

Advancing the Human Right to Health offers a prospective on the global response to one of
the greatest moral, legal, and public health challenges of the 21st century-achieving the …

Community‐centric approaches to engage underrepresented populations—including
community engagement, community‐level consent practices, and capacity development for …

Despite evidence that pharmacogenetics can improve tamoxifen pharmacotherapy, there
are few studies with American Indian and Alaska Native (AIAN) people. We examined …

Objectives Cytochrome P450 enzymes play a dominant role in drug elimination and
variation in these genes is a major source of interindividual differences in drug response …

Indigenous North American populations, including American Indian and Alaska Native
peoples in the United States, the First Nations, Métis and Inuit peoples in Canada and …

Amid the rapid growth of precision medicine and biobanking initiatives, there have been few
efforts at cataloging the implications of these initiatives for Indigenous communities. A …

Genomic information is poised to play an increasing role in clinical care, extending beyond
highly penetrant genetic conditions to less penetrant genotypes and common disorders. But …