Metaplasticity: tuning synapses and networks for plasticity
WC Abraham - Nature Reviews Neuroscience, 2008 - nature.com
Synaptic plasticity is a key component of the learning machinery in the brain. It is vital that
such plasticity be tightly regulated so that it occurs to the proper extent at the proper time …
such plasticity be tightly regulated so that it occurs to the proper extent at the proper time …
Regulatory mechanisms of AMPA receptors in synaptic plasticity
VA Derkach, MC Oh, ES Guire… - Nature Reviews …, 2007 - nature.com
Activity-dependent changes in the strength of excitatory synapses are a cellular mechanism
for the plasticity of neuronal networks that is widely recognized to underlie cognitive …
for the plasticity of neuronal networks that is widely recognized to underlie cognitive …
Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease
A Nobili, EC Latagliata, MT Viscomi… - Nature …, 2017 - nature.com
Alterations of the dopaminergic (DAergic) system are frequently reported in Alzheimer's
disease (AD) patients and are commonly linked to cognitive and non-cognitive symptoms …
disease (AD) patients and are commonly linked to cognitive and non-cognitive symptoms …
Cell-type-specific optogenetic stimulation of the locus coeruleus induces slow-onset potentiation and enhances everyday memory in rats
D Tse, L Privitera, AC Norton… - Proceedings of the …, 2023 - National Acad Sciences
Memory formation is typically divided into phases associated with encoding, storage,
consolidation, and retrieval. The neural determinants of these phases are thought to differ …
consolidation, and retrieval. The neural determinants of these phases are thought to differ …
New medications for drug addiction hiding in glutamatergic neuroplasticity
PW Kalivas, ND Volkow - Molecular psychiatry, 2011 - nature.com
The repeated use of drugs that directly or indirectly stimulate dopamine transmission carry
addiction liability and produce enduring pathological changes in the brain circuitry that …
addiction liability and produce enduring pathological changes in the brain circuitry that …
Glutamatergic substrates of drug addiction and alcoholism
JT Gass, MF Olive - Biochemical pharmacology, 2008 - Elsevier
The past two decades have witnessed a dramatic accumulation of evidence indicating that
the excitatory amino acid glutamate plays an important role in drug addiction and …
the excitatory amino acid glutamate plays an important role in drug addiction and …
Dopamine and extinction: a convergence of theory with fear and reward circuitry
Research on dopamine lies at the intersection of sophisticated theoretical and
neurobiological approaches to learning and memory. Dopamine has been shown to be …
neurobiological approaches to learning and memory. Dopamine has been shown to be …
AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine
ME Wolf, CR Ferrario - Neuroscience & Biobehavioral Reviews, 2010 - Elsevier
This review focuses on cocaine-induced postsynaptic plasticity in the nucleus accumbens
(NAc) involving changes in AMPA receptor (AMPAR) transmission. First, fundamental …
(NAc) involving changes in AMPA receptor (AMPAR) transmission. First, fundamental …
Dopamine-regulated microRNA MiR-181a controls GluA2 surface expression in hippocampal neurons
R Saba, PH Störchel, A Aksoy-Aksel… - … and cellular biology, 2012 - Taylor & Francis
The dynamic expression of AMPA-type glutamate receptors (AMPA-R) at synapses is a key
determinant of synaptic plasticity, including neuroadaptations to drugs of abuse. Recently …
determinant of synaptic plasticity, including neuroadaptations to drugs of abuse. Recently …
Regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking through PKA phosphorylation of the Glu receptor 1 subunit
HY Man, Y Sekine-Aizawa… - Proceedings of the …, 2007 - National Acad Sciences
α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors mediate the
majority of excitatory synaptic transmission in the brain. Recent studies have shown that …
majority of excitatory synaptic transmission in the brain. Recent studies have shown that …