[HTML][HTML] Recent advancements of nanoparticles application in cancer and neurodegenerative disorders: At a glance

MM Rahman, MR Islam, S Akash… - Biomedicine & …, 2022 - Elsevier
Nanoscale engineering is one of the innovative approaches to heal multitudes of ailments,
such as varieties of malignancies, neurological problems, and infectious illnesses …

Targeting the transferrin receptor for brain drug delivery

KB Johnsen, A Burkhart, LB Thomsen… - Progress in …, 2019 - Elsevier
Obtaining efficient drug delivery to the brain remains the biggest challenge for the
development of therapeutics to treat diseases of the central nervous system. The main …

Nano carrier drug delivery systems for the treatment of neuropsychiatric disorders: Advantages and limitations

Y Zorkina, O Abramova, V Ushakova, A Morozova… - Molecules, 2020 - mdpi.com
Neuropsychiatric diseases are one of the main causes of disability, affecting millions of
people. Various drugs are used for its treatment, although no effective therapy has been …

The link between oxidative stress, mitochondrial dysfunction and neuroinflammation in the pathophysiology of Alzheimer's disease: therapeutic implications and future …

MC Jurcău, FL Andronie-Cioara, A Jurcău, F Marcu… - Antioxidants, 2022 - mdpi.com
Alzheimer's disease (AD), the most common form of dementia, has increasing incidence,
increasing mortality rates, and poses a huge burden on healthcare. None of the currently …

Nanoformulation properties, characterization, and behavior in complex biological matrices: Challenges and opportunities for brain-targeted drug delivery applications …

V Agrahari, PA Burnouf, T Burnouf… - Advanced Drug Delivery …, 2019 - Elsevier
Nanocarriers (synthetic/cell-based have attracted enormous interest for various therapeutic
indications, including neurodegenerative disorders. A broader understanding of the impact …

PEGylated polylactide (PLA) and poly (lactic-co-glycolic acid)(PLGA) copolymers for the design of drug delivery systems

DR Perinelli, M Cespi, G Bonacucina… - Journal of …, 2019 - Springer
Background PEGylated polylactide (PLA) and poly (lactic-co-glycolic acid)(PLGA)
copolymers are biodegradable polyesters, widely employed in the last decades for the …

Influence of nanoparticle size on blood–brain barrier penetration and the accumulation of anti-seizure medicines in the brain

Q Meng, H Meng, Y Pan, J Liu, J Li, Y Qi… - Journal of Materials …, 2022 - pubs.rsc.org
Anti-seizure medicines constitute a common yet important modality to treat epilepsy.
However, some of them are associated with serious side effects including hepatotoxicity and …

Electrically controlled drug release of donepezil and BiFeO3 magnetic nanoparticle-loaded PVA microbubbles/nanoparticles for the treatment of Alzheimer's disease

S Cesur, ME Cam, FS Sayin, O Gunduz - Journal of Drug Delivery Science …, 2022 - Elsevier
Nanocarriers are used to deliver bioactive substances in the treatment of neurodegenerative
diseases such as Alzheimer's disease (AD). These nanocarriers have shown many benefits …

Novel therapeutic strategies for Alzheimer's disease: Implications from cell-based therapy and nanotherapy

H Derakhshankhah, S Sajadimajd, S Jafari… - … , Biology and Medicine, 2020 - Elsevier
Alzheimer's disease (AD) is a multifactorial neurodegenerative disease which leads to
progressive dysfunction of cognition, memory and learning in elderly people. Common …

Neutrophil‐based delivery systems for nanotherapeutics

Y Han, R Zhao, F Xu - Small, 2018 - Wiley Online Library
Neutrophils, the most abundant leukocytes (50–70% of the total leukocytes in circulation),
are the major type of cells recruited to sites of inflammation during infection and …