Cancer is a disorder that rigorously affects the human population worldwide. There is a
steady demand for new remedies to both treat and prevent this life-threatening sickness due …

Anemia is a common complication of myelosuppressive chemotherapy that results in a
decreased functional capacity and quality of life (QOL) for cancer patients. Severe anemia is …

Purpose Docetaxel has shown activity in elderly patients with advanced non–small-cell lung
cancer (NSCLC). This randomized phase III trial evaluated the efficacy and safety of …

In past years, there has been considerable pessimism over the role of chemotherapy in non-
small cell lung cancers. The pessimism was largely derived from the fact that alkylating …

The majority of data available for vinorelbine are based upon iv administration of the drug.
Initial phase I studies of vinorelbine were performed in France, and the dose-limiting toxicity …

Plants and natural compounds have been widely recognized to have potential for the
prevention of cancer progression and as complementary or standalone treatments for …

The biological and cytotoxic activity of alkaloids derived from the Madagascan periwinkle
(vinca rosea) has been established for many years (1). However, the low yields of active …

To review the available published data regarding the incidence, mechanisms of
pathogenesis, clinical presentations and management of pneumonitis caused by anti-cancer …

Drugs have been implicated in lung injury as a result of direct pharmacological action,
persistence or metabolism in the tissue, or via the production of a reactive metabolite or …

More than 30% of lung cancers arise in patients aged 70 years or more; however, because
elderly patients are not considered to tolerate chemotherapy, they are generally excluded …