Chronic lymphocytic leukaemia
L Scarfò, AJM Ferreri, P Ghia - Critical reviews in oncology/hematology, 2016 - Elsevier
Chronic lymphocytic leukaemia (CLL) is the most common leukaemia among the adults in
the Western World. CLL (and the corresponding nodal entity small lymphocytic lymphoma …
the Western World. CLL (and the corresponding nodal entity small lymphocytic lymphoma …
Immunophenotyping of acute leukemia and lymphoproliferative disorders: a consensus proposal of the European LeukemiaNet Work Package 10
MC Béné, T Nebe, P Bettelheim, B Buldini, H Bumbea… - Leukemia, 2011 - nature.com
Abstract The European LeukemiaNet (ELN), workpackage 10 (WP10) was designed to deal
with diagnosis matters using morphology and immunophenotyping. This group aimed at …
with diagnosis matters using morphology and immunophenotyping. This group aimed at …
FDA approval: ibrutinib for patients with previously treated mantle cell lymphoma and previously treated chronic lymphocytic leukemia
RA de Claro, KM McGinn, N Verdun, SL Lee… - Clinical Cancer …, 2015 - AACR
Abstract On November 13, 2013, the FDA granted accelerated approval to ibrutinib
(IMBRUVICA capsules; Pharmacyclics, Inc.) for the treatment of patients with mantle cell …
(IMBRUVICA capsules; Pharmacyclics, Inc.) for the treatment of patients with mantle cell …
Chronic lymphocytic leukemia
P Ghia, AJM Ferreri, F Caligaris-Cappio - Critical reviews in oncology …, 2007 - Elsevier
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the western
world and is due to the accumulation of mature B lymphocytes in the peripheral blood, bone …
world and is due to the accumulation of mature B lymphocytes in the peripheral blood, bone …
Cell proliferation and death: forgotten features of chronic lymphocytic leukemia B cells
N Chiorazzi - Best practice & research Clinical haematology, 2007 - Elsevier
Chronic lymphocytic leukemia (CLL) results from an accumulation of abnormal B cells due to
an imbalance between birth and death rates such that the former exceeds the latter. This …
an imbalance between birth and death rates such that the former exceeds the latter. This …
Microenvironmental interactions and survival of CLL B-cells
I Munk Pedersen, J Reed - Leukemia & lymphoma, 2004 - Taylor & Francis
Chronic Lymphocytic Leukemia (CLL) B cells display characteristics consistent with a defect
in programmed cell death (apoptosis) and exhibit prolonged survival in vivo. When …
in programmed cell death (apoptosis) and exhibit prolonged survival in vivo. When …
Short telomeres are associated with genetic complexity, high-risk genomic aberrations, and short survival in chronic lymphocytic leukemia
G Roos, A Kröber, P Grabowski… - Blood, The Journal …, 2008 - ashpublications.org
Telomere length is associated with mutation status of the immunoglobulin heavy chain
variable (IGHV) gene and clinical course in B-cell chronic lymphocytic leukemia (B-CLL). In …
variable (IGHV) gene and clinical course in B-cell chronic lymphocytic leukemia (B-CLL). In …
Differences in gene expression between B-cell chronic lymphocytic leukemia and normal B cells: a meta-analysis of three microarray studies
J Wang, KR Coombes, WE Highsmith… - …, 2004 - academic.oup.com
Motivation: A major focus of current cancer research is to identify genes that can be used as
markers for prognosis and diagnosis, and as targets for therapy. Microarray technology has …
markers for prognosis and diagnosis, and as targets for therapy. Microarray technology has …
[HTML][HTML] Chronic lymphocytic leukemia B-cell normal cellular counterpart: clues from a functional perspective
W Darwiche, B Gubler, JP Marolleau… - Frontiers in …, 2018 - frontiersin.org
Chronic lymphocytic leukemia (CLL) is characterized by the clonal expansion of small
mature-looking CD19+ CD23+ CD5+ B-cells that accumulate in the blood, bone marrow …
mature-looking CD19+ CD23+ CD5+ B-cells that accumulate in the blood, bone marrow …
Survival response to B-cell receptor ligation is restricted to progressive chronic lymphocytic leukemia cells irrespective of Zap70 expression
PA Deglesne, N Chevallier, R Letestu… - Cancer research, 2006 - AACR
Despite very similar gene expression profiles, the clinical course of B-cell chronic
lymphocytic leukemia (B-CLL) is heterogeneous. Immunoglobulin VH (IgVH) mutational …
lymphocytic leukemia (B-CLL) is heterogeneous. Immunoglobulin VH (IgVH) mutational …