Examining neural etiologic factors' role in the decline of neuromuscular function with aging
is essential to our understanding of the mechanisms underlying sarcopenia, the age …

Background Heart failure (HF) is a main consequence of cardiovascular diseases
worldwide. Abnormal expression levels of microRNAs (miRNAs) in HF are observed in …

In addition to traditional drugs, such as enzyme inhibitors, receptor agonists/antagonists,
and protein‐protein interaction inhibitors as well as genetic technology, such as RNA …

MicroRNAs (miRNAs/miRs) are sensitive biomarkers and endogenous repressors of gene
expression by decreasing mRNA stability and interfering with mRNA translation. Despite a …

This study was designed to determine whether and how the sympathetic nervous system
(SNS) regulates motoneuron axon function and neuromuscular transmission in young (3–4 …

Abstract Backgroud Xinbao Pill (XBP) is extensively used in the adjuvant treatment of
chronic heart failure in China. However, the pharmacological effect and underlying …

Abstract Purpose of Review Heart failure is a severe clinical syndrome with complex and
unclarified mechanisms, and it poses a serious threat to human health. MicroRNA, a non …

Background MicroRNA (miRNA) has been shown to play a key role in the occurrence and
progression of diseases, making uncovering miRNA-disease associations vital for disease …

Aims Declining cellular functional capacity resulting from stress or ageing is a primary
contributor to impairment of myocardial performance. Molecular pathway regulation of …

Doxorubicin (DOX), a broad-spectrum chemotherapy drug, is widely applied to the treatment
of cancer; however, DOX-induced cardiotoxicity (DIC) limits its clinical therapeutic utility …