A review of Glycogen Synthase Kinase-3 (GSK3) inhibitors for cancers therapies
The intricate molecular pathways governing cancer development and progression have
spurred intensive investigations into novel therapeutic targets. Glycogen Synthase Kinase-3 …
spurred intensive investigations into novel therapeutic targets. Glycogen Synthase Kinase-3 …
[HTML][HTML] Radioiodine therapy in advanced differentiated thyroid cancer: Resistance and overcoming strategy
Y Liu, J Wang, X Hu, Z Pan, T Xu, J Xu, L Jiang… - Drug Resistance …, 2023 - Elsevier
Thyroid cancer is the most prevalent endocrine tumor and its incidence is fast-growing
worldwide in recent years. Differentiated thyroid cancer (DTC) is the most common …
worldwide in recent years. Differentiated thyroid cancer (DTC) is the most common …
LncRNA GLTC targets LDHA for succinylation and enzymatic activity to promote progression and radioiodine resistance in papillary thyroid cancer
L Shi, R Duan, Z Sun, Q Jia, W Wu, F Wang… - Cell Death & …, 2023 - nature.com
Dysregulation of long noncoding RNAs (lncRNAs) has been associated with the
development and progression of many human cancers. Lactate dehydrogenase A (LDHA) …
development and progression of many human cancers. Lactate dehydrogenase A (LDHA) …
[HTML][HTML] HIF-1α/YAP signaling rewrites glucose/iodine metabolism program to promote papillary thyroid cancer progression
H Song, Z Qiu, Y Wang, C Xi, G Zhang… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Background: The management of aggressive and progressive metastatic papillary thyroid
cancer (PTC) is very difficult. An inverse relationship between radioiodine and F-18 …
cancer (PTC) is very difficult. An inverse relationship between radioiodine and F-18 …
[HTML][HTML] Supramolecular nanofibers co-loaded with dabrafenib and doxorubicin for targeted and synergistic therapy of differentiated thyroid carcinoma
P Chen, X Cai, G Mu, Y Duan, C Jing, Z Yang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Rationale: Although surgery, radioiodine therapy, and thyroid hormone therapy are the
primary clinical treatments for differentiated thyroid carcinoma (DTC), effective therapy for …
primary clinical treatments for differentiated thyroid carcinoma (DTC), effective therapy for …
Molecular imaging and theragnostics of thyroid cancers
L Giovanella, D Deandreis, A Vrachimis, A Campenni… - Cancers, 2022 - mdpi.com
Simple Summary According to the American Cancer Society, approximately 53,000 new
cases of thyroid cancer were diagnosed and more than 2200 people died from the disease …
cases of thyroid cancer were diagnosed and more than 2200 people died from the disease …
[HTML][HTML] Roles of hepatic stellate cells in NAFLD: From the perspective of inflammation and fibrosis
M Wang, L Li, Y Xu, J Du, C Ling - Frontiers in Pharmacology, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) has become one of the most common diseases
and severe problems worldwide because of the global increase in obesity, dyslipidemia …
and severe problems worldwide because of the global increase in obesity, dyslipidemia …
IGF2BP2-dependent activation of ERBB2 signaling contributes to acquired resistance to tyrosine kinase inhibitor in differentiation therapy of radioiodine-refractory …
R Sa, R Liang, X Qiu, Z He, Z Liu, L Chen - Cancer letters, 2022 - Elsevier
Acquired drug resistance represents a major obstacle to tyrosine kinase inhibitor (TKI)-
induced differentiation therapy of radioiodine-refractory papillary thyroid cancer (RR-PTC); …
induced differentiation therapy of radioiodine-refractory papillary thyroid cancer (RR-PTC); …
Strategies for radioiodine treatment: what's new
C Sparano, S Moog, J Hadoux, C Dupuy, A Al Ghuzlan… - Cancers, 2022 - mdpi.com
Simple Summary Radioactive iodine treatment is the oldest targeted therapy for
differentiated thyroid cancer. It can be used for normal thyroid remnant ablation (in order to …
differentiated thyroid cancer. It can be used for normal thyroid remnant ablation (in order to …
[HTML][HTML] Molecular basis and targeted therapy in thyroid cancer: progress and opportunities
L Zhang, Q Feng, J Wang, Z Tan, Q Li, M Ge - Biochimica et Biophysica …, 2023 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. Surgery,
chemotherapy, radiotherapy, and radioactive iodine (RAI) therapy are the standard TC …
chemotherapy, radiotherapy, and radioactive iodine (RAI) therapy are the standard TC …