Solidification to improve the biopharmaceutical performance of SEDDS: Opportunities and challenges
Self-emulsifying drug delivery systems (SEDDS) offer potential for overcoming the inherent
slow dissolution and poor oral absorption of hydrophobic drugs by retaining them in a …
slow dissolution and poor oral absorption of hydrophobic drugs by retaining them in a …
Colloidal aspects of dispersion and digestion of self-dispersing lipid-based formulations for poorly water-soluble drugs
Self-dispersing lipid-based formulations, particularly self-microemulsifying drug delivery
systems (SMEDDS) have gained an increased interest in recent times as a means to …
systems (SMEDDS) have gained an increased interest in recent times as a means to …
Self assembled materials: design strategies and drug delivery perspectives
Self assembly of small molecules in complex supramolecular structures provides a new
avenue in the development of materials for drug delivery applications. Owing to the low …
avenue in the development of materials for drug delivery applications. Owing to the low …
Advances in lipid carriers for drug delivery to the gastrointestinal tract
Lipid-based formulations have re-emerged as oral drug delivery systems. Advances in the
techniques to evaluate the in vivo fate of the formulations, together with an improved …
techniques to evaluate the in vivo fate of the formulations, together with an improved …
Design and optimization of pioglitazone hydrochloride self-nanoemulsifying drug delivery system (SNEDDS) incorporated into an orally disintegrating tablet
Pioglitazone Hydrochloride (PGZ) suffers from poor aqueous solubility. The aim of this
research was to design orally disintegrating tablets with self-nanoemulsifying properties (T …
research was to design orally disintegrating tablets with self-nanoemulsifying properties (T …
Recent advances in self-emulsifying drug delivery systems (SEDDS)
B Singh, S Beg, RK Khurana… - Critical Reviews™ in …, 2014 - dl.begellhouse.com
One of the biggest challenges confronting the contemporary drug delivery science today is
to improve on the oral bioavailability of a vast number of drugs exhibiting poor and …
to improve on the oral bioavailability of a vast number of drugs exhibiting poor and …
Oral formulation strategies to improve the bioavailability and mitigate the food effect of abiraterone acetate
Abiraterone acetate, marketed as Zytiga®, is an antiandrogen medication used in the
treatment of prostate cancer. Abiraterone acetate is a BCS Class IV compound associated …
treatment of prostate cancer. Abiraterone acetate is a BCS Class IV compound associated …
Self-nanoemulsifying ramipril tablets: A novel delivery system for the enhancement of drug dissolution and stability
KF Alhasani, M Kazi, MA Ibrahim… - International journal …, 2019 - Taylor & Francis
Background: Ramipril (RMP) suffers from poor aqueous solubility along with sensitivity to
mechanical stress, heat, and moisture. The aim of the current study is to improve RMP …
mechanical stress, heat, and moisture. The aim of the current study is to improve RMP …
Novel nanostructured solid materials for modulating oral drug delivery from solid-state lipid-based drug delivery systems
Lipid-based drug delivery systems (LBDDS) have gained significant attention in recent
times, owing to their ability to overcome the challenges limiting the oral delivery of poorly …
times, owing to their ability to overcome the challenges limiting the oral delivery of poorly …
Nanomedicine for the effective and safe delivery of non-steroidal anti-inflammatory drugs: A review of preclinical research
The toxicity of nonsteroidal anti-inflammatory drugs (NSAIDs) is one of the major limitations
to their long-term use in the treatment of chronic inflammatory conditions. This review …
to their long-term use in the treatment of chronic inflammatory conditions. This review …