[HTML][HTML] The mir-423-5p/MMP-2 axis regulates the nerve growth factor-induced promotion of chondrosarcoma metastasis
HE Tzeng, SL Lin, LA Thadevoos, CY Ko, JF Liu… - Cancers, 2021 - mdpi.com
Simple Summary A chondrosarcoma is a common tumor of the bone that has a high
propensity to metastasize to distant organs. The effects of NGF in a chondrosarcoma are not …
propensity to metastasize to distant organs. The effects of NGF in a chondrosarcoma are not …
[HTML][HTML] Isothermal circular strand displacement–based assay for microRNA detection in liquid biopsy
N Bellassai, R D'Agata, G Spoto - Analytical and Bioanalytical Chemistry, 2022 - Springer
Extracellular miRNAs are promising targets for developing new assays for the early
diagnosis and prognosis of diseases based on liquid biopsy. The detection of miRNAs in …
diagnosis and prognosis of diseases based on liquid biopsy. The detection of miRNAs in …
[HTML][HTML] TMT quantitative proteomics reveals key proteins relevant to microRNA-1-mediated regulation in osteoarthritis
P Jiang, D Liang, H Wang, R Zhou, X Che, L Cong… - Proteome Science, 2023 - Springer
Osteoarthritis (OA) is the second-commonest arthritis, but pathogenic and regulatory
mechanisms underlying OA remain incompletely understood. Here, we aimed to identify the …
mechanisms underlying OA remain incompletely understood. Here, we aimed to identify the …
[HTML][HTML] Joint Tissue Protective and Immune-Modulating miRNA Landscape of Mesenchymal Stromal Cell-Derived Extracellular Vesicles under Different Osteoarthritis …
E Ragni, C Perucca Orfei, F Sinigaglia, L de Girolamo - Pharmaceutics, 2022 - mdpi.com
In regenerative medicine related to orthopedic conditions, mesenchymal stromal cells
(MSCs) and their extracellular vesicles (EVs) have been proposed as innovative clinical …
(MSCs) and their extracellular vesicles (EVs) have been proposed as innovative clinical …
[HTML][HTML] ROS-induced imbalance of the miR-34a-5p/SIRT1/p53 axis triggers chronic chondrocyte injury and inflammation
M Zhou, B Liu, HM Ye, JN Hou, YC Huang, P Zhang… - Heliyon, 2024 - cell.com
Osteoarthritis is a chronic degenerative disease based on the degeneration and loss of
articular cartilage. Inflammation and aging play an important role in the destruction of the …
articular cartilage. Inflammation and aging play an important role in the destruction of the …
Comparative Analysis of Short‐Term and Long‐Term Clinical Efficacy of Mesenchymal Stem Cells from Different Sources in Knee Osteoarthritis: A Network Meta …
QX Ding, X Wang, TS Li, YF Li, WY Li… - Stem Cells …, 2024 - Wiley Online Library
Background. Joint articular injection of mesenchymal stem cells (MSCs) has emerged as a
novel treatment approach for osteoarthritis (OA). However, the effectiveness of MSCs …
novel treatment approach for osteoarthritis (OA). However, the effectiveness of MSCs …
[HTML][HTML] Construction and analysis of a lncRNA–miRNA–mRNA competing endogenous RNA network from inflamed and normal synovial tissues after anterior cruciate …
X Xiao, X Yang, S Ren, C Meng, Z Yang - Frontiers in Genetics, 2022 - frontiersin.org
Background: Despite ample evidence demonstrating that anterior cruciate ligament (ACL)
and meniscus tears are associated with posttraumatic osteoarthritis (PTOA) development …
and meniscus tears are associated with posttraumatic osteoarthritis (PTOA) development …
Analysis of the regulatory role of miR-34a-5p/PLCD3 in the progression of osteoarthritis
P Ying, Y Xu, X Jiang, K Wang, Y Xue, Q Wang… - Functional & Integrative …, 2023 - Springer
Osteoarthritis is a heterogeneous disease with a complex etiology. However, there is no
effective treatment strategy at present. The purpose of this study was to explore the miRNA …
effective treatment strategy at present. The purpose of this study was to explore the miRNA …
Comparison of miRNA cargo in human adipose-tissue vs. amniotic-membrane derived mesenchymal stromal cells extracellular vesicles for osteoarthritis treatment
R Enrico, CP Orfei, A Papait… - EXTRACELLULAR …, 2021 - publicatt.unicatt.it
Aim: Mesenchymal stromal cells (MSCs) emerged as a promising therapeutic option for
osteoarthritis (OA) management, in particular those isolated from adipose tissue (hASCs) …
osteoarthritis (OA) management, in particular those isolated from adipose tissue (hASCs) …
Identification of diagnostic markers in synovial tissue of osteoarthritis by weighted gene coexpression network
YS Zhu, H Yan, TT Mo, JN Zhang, C Jiang - Biochemical Genetics, 2023 - Springer
Osteoarthritis (OA) is a serious threat to human health. However, the etiology and
pathogenesis of the disease are not fully understood. Most researchers believe that the …
pathogenesis of the disease are not fully understood. Most researchers believe that the …